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Pharm Test 4 > Chemo and OTC drugs/ supplements > Flashcards

Chemo and OTC drugs/ supplements Flashcards

1
Q

what is the largest and most diverse antineoplastic and what does it do?

A

alkylating agent:

  1. interferes by crosslinking
  2. makes abnormal base pairing
  3. DNA strand breakage
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2
Q

example of alkylating agent

A

nitrosureas- crosses the BBB

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3
Q

MOA of cisplatin

A

enters cell

forms highly reactive platinum complexes

cross links

dna damage

inhibits cell proliferation

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4
Q

which cancers are more liquids

A

leukemias

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5
Q

which cancers are more solids

A

lymphomas

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6
Q

what is the most common type of cancer?

A

carcinoma
fast growing

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7
Q

what is sarcoma?

A

slow growing type of cancer

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8
Q

MOA of methotrexate?

A

dihydrofolate reductase- interferes with DNA and RNA synthesis

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9
Q

what class is 6-MP and 5-FU in?

A

antimetabolites

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10
Q

what class is vincristine, and paclitaxel (Taxol) in?

A

plant based

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11
Q

what class is dactinomycin, doxorubicin, and bleomycin in?

A

antibiotics

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12
Q

what class is corticosteroids, tamoxifen, and fulvestrant in?

A

Hormonal agents

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13
Q

what class is -ibs and -mabs in?

A

miscellaneous

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14
Q

what is echinacea used for?

A

stimulation of the immune system, anti inflammatory

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15
Q

what is garlic supposed to do?

A

HMG coa reductase inhibitor

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16
Q

what does ginkgo do?

A

improves blood flow, free radical scavenger

17
Q

what does st. johns wart do?

A

antidepressant

18
Q

what is ginseng used for?

A

multiple claims (memory, immune, analgesia ect.)

19
Q

what is milk thistle used for

A

hepatoxicity

20
Q

what is saw palmetto used for?

A

BPH

21
Q

what is kava kava used for

A

anxiety, muscle relaxant, sedative

22
Q

what is kombucha tea used for?

A

yeast and bacteria
bp, cancer, gi health

23
Q

what is aloe used for?

A

laxative, burn ointment

24
Q

what is black cohosh used for?

A

menstrual discomfort

Pharm Test 4 (9 decks)

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