Ophtha Flashcards
Marker of limbal stem cells
ABCG2
Universal marker of stem cells
CD34
Corneoscleral jn is aka
Limbus
Epithelium of cornea is made up of
Non keratinised stratified squamous epithelium
M/c collagen in Bowmans membrane
Type 1
M/c Ground substance in Bowmans membrane
Keratin sulphate
Most metabolically active layer of cornea
Endothelium
Normal endothelial cell count
2400-3000 cells/mm2
How to measure endothelial cell count
Specular microscopy
Instrument used to measure corneal sensation
Aesthesiometer
Micro cornea associated with..
Cong. Rubella syndrome
Macro cornea associated with
Marfan n Down syndrome
Instrument to measure corneal thickness
Pachymeter
____measures the radius of curvature of ant. Corneal surface
Keratometry
Corneal topography measured by
Placedo disk
Thinnest sclera
Post to insertion of recti
Thickest sclera
Around optic nerve
Thinnest part of Iris
Root
M/c site for TRAUMATIC DETACHMENT of Iris
Root
Thickest part of Iris
Collarette
Normal cup disk ratio
< or =to .3
Most sensitive part of retina
Fovea Centralis
Highest visual acuity seen at
Fovea centralis
Point of penetration of Intravitreal inj.
Ant to serrata
Refractive index of cornea
1.376
Refractive Power of cornea
43 Diapter
Refractive power of eyeball
58.6 D
Blood supply of macula
Dual- Central retinal Artery n cilioretinal artery
Central retinal artery supplies
Inner 6 layers and macula
Outer 4 layers of the retina are supplied by..
Short branch of Post. Ciliary artery
Refractive index of lens nucleus
1.406 (Highest RI of eye)
RI of lens cortex
1.386
Munson sign seen in
Keratoconus
Gold standard diagnostic method for keratoconus
Corneal topography using Placedo disk
TOC for Keratoconus
C3R/CCC
MCC of bac. Corneal ulcer Worldwide
Staph. Aureus
MCC of Bac. Corneal ulcer in India
Strep. Pneumoniae/pneumococcus
MCC of bac. Corneal ulcer in Contact lens users
Pseudomonas
What causes cracked windshield ulcer??
Post LASIK Surgery
Pin head ulcer/ Wreath pattern
Nocardia
Bac. which invade intact corneal epithelium
GIrLS Cornea G-Neisseria gonorrhoea/ Meningitidis I-Influenzae Haemophilous L- Listeria S- Shigella Cornea- Cornybacteriuum diphtheriae
MCC(organism) causing Fungal Corneal Ulcer
Aspergillus fumigatus
The Character of hypopion in bac. and Fungal corneal ulcer
Bac.-sterile & mobile
Fungal- Non sterile & Immobile
C/F of Fungal corneal ulcer
RED FISH R- Rolled out edges E- Everted D- Dry looking F- Feathery Margin I- Immune ring of Wesley S- Satellite Lesions H- Hypopion
Organism causing Viral corneal ulcer
HSV-keratitis
T/t of Disciform keratitis
Acyclovir+steroids
Investigation of Acanthamoeba keratitis
Non nutrient agar enriched with e coli
T/t of Acanthamoeba keratitis
PHMB 0.02%
Polyhexamethylenebiguanide
Storage media for preserving cornea
For 48h, 2 weeks ,35 days
+4 degree moist chamber
Mac karry kauffman media
Cryopreservation at -700 degree
Sunflower cataract seen in
Wilson disease + Chalcosis
Snowflake cataract ?
Hyperglycemia related activation of sorbitol of sorbitol pathway.
Which cataract causes more loss of vision in daylight?
Nuclear cataract
Which cataract causes more loss of vision in dimlight
Cortical cataract
Earliest sign of cortical cataract
Formation of vacuoles + water cleft
Which cataract causes max.visual loss?
Cupuliform/PSC Cataract
Which cataract is diagnosed with reducing sugars in urine?
Galactosemia
The only reversible cataract is
Galactosemia asso. Cataract
Which is the oil droplet cataract
Galactosemia
Cataract occurs due to IR rays.. is..
Glans blower cataract
Causes of Complicated Cataract
RAMU R-Retinitis Pigmentosa A-Angle closure Glaucoma M—Myopia (high) U- Uveitis (MCC)
In which surgery we incise a 2.2-3.2mm deep incision
Phacoemulsification
Wavelength of FLACS
1053nm
M/c used formula for calculating IOL
SRK 2
Best site for IOL Implantation
Ciliary bag
By which material, Anterior chamber IOL is made of
PMMA
PolyMethyleneMethAcrylase
PCIOL is made of which material
Rigid-PMMA
Foldable-Acrylic, Collamer(HEXA), Silicon
M/c complication of cataract surgery
After cataract or Post capsular opacification
Types of complication of cat. Sx
ELSCHNIG Pearls
Ring of sommering
Tx of complication of cat.sx
ND:YAG Laser capsulotomy
Wavelength: 1064nm
MCC in Acute post op Endophthalmitis
Staph.epidermidis
M/c cause of Late onset post op Endophthalmitis
Propionibacterium Acnes
Hallmark of Endophthalmitis
Amarotic cat eye reflex or leucokoria (white pupillary reflex)
T/t of Endophthalmitis if vision prsnt
Vancomycin + Ceftazidime
What should be administered prior to surgery of cataract to avoid Endophthalmitis
Povidone iodine(5%)
Severe loss of vision is seen in which congenital cataract
Primary congenital cataract
Most common congenital cataract overall
Blue dot cataract
Treatment of the congenital cataract
Lens aspiration + anterior vitrectomy + posterior capsulotomy + IOL implantation
What are the causes of Ectopia Lents
Most common-blunt trauma Hyper mature senile cataract Familial autosomal dominant ANIRIDIA MARFAN SYNDROME:Most commin syndromic asso. with syndromic cause
Direction of Ectopic Lents
Superotemporal
What is the direction of the lens displacement in Ectopic lents
Superotemporal
Direction of displacement of lens in familial homocystinuria
Inferonasal
Causes of anterior lenticonus
Spina bifid
Albort syndrome
Waardenburg syndrome
What are the causes of posterior lenticonus
LOWE Syndrome
what are the structures which can be appreciated from posterior to anterior when doing a gonioscopy
Cant see this stuff Ciliary body band Scleral Spur TM Schwallor’s line
Frequent changes in the presbyopic glasses is seen in
POAG aka Simple closure glaucoma
Frequent changes in the myopic glasses is seen in
Cataract
Genes for POAG
Optineurin
Myoc
Byonetting sign
Double angulation of BV in eyes
Clinically significant VFD
Paracentral scotoma
Which all class of drugs we are using for the POAG
Prostaglandin Analogues
Beta blockers
Alpha Agonist
Carbonic anhydrase inhibitors
Which class of drugs causes eyelid retraction
Alpha agonist
What class of drug is contraindicated in children less than two years for POAG
Alpha Agonist
The drugs which is not given topically for POAG
Acetazolamide
C/I in sulfa allergy
Brinzolamide
Dorzolamide
Surgical treatment for POAG
Trabeculectomy
Which test is used to differentiate the halos between cataract and glaucoma
Fincham test
Earliest symptom of cong.glaucoma
Photophobia
Most common symptom of cong. Glaucoma
Lacrimation
Cause of Malignant glaucoma
Due to incisional surgery, Laser Sx for Glaucoma or Cataract
Most common manifestation in blunt trauma
Hyphema
What change pupil will have more blunt trauma
IRIDODIALYSIS
IRIDODONESIS
What change can be appreciated while having a blunt trauma in lens
Ectopia lentis
Rosette shaped cataract
Vossius ring
Posterior segment, what change in blunt trauma
Berlins edema
Cherry red spots
Blow out #
Floor of Orbit
Xray-tear drop sign in antrum
Orbital Roof #
Panda/raccoon eye
Which instrument measures proptosis
Hertol’s Exophthalmometer
MCC of proptosis in adults
U/L or B/L Thyroid associated ophthalmopathy
MCC of proptosis in children
U/L Orbital cellulitis
B/L Neuroblastoma
Staring appearance
KOCHER’S SIGN
Lid lag in Thyroid associated ophthalmopathy shows what sign
VONGRAEFFE
Most common clinical feature of Thyroid associated ophthalmopathy
Lid retraction aka DALRYMPLE Sign
Deep AC glaucoma is seen in
Young ,myopic
Shallow AC Glaucoma seen in
Elderly, female, hypermetropic
Investigation of retina
Ophthalmoloscopy B-Scan USG OCT(Optical coherence Tomography) FFA(Fundus fluorescence Angiography) ERG
Increased levels of HbA1c is seen in
Diabetic retinopathy
Earliest change of Diabetic retinopathy
Loss of pericytes
Hallmark of diabetic retinopathy
Neovascularisation of retina
TOC of Diabetic retinopathy
PRP-Pan Retinal Photocoagulation
Anti-VEGF Drugs
Ranibizumab
Bevacizumab
Aflibucept
Which is the most common cause of LOV in NPDR
Diabetic Macular Edema
MCC of LOV in PDR
Vitreous hemorrhage
MCC of blindness in DR
Retinal Detachment
Tomato ketchup appearance seen in
CRVO Ischemic
Hollenhorst plaque seen in
CRAO
Cherry Red spot seen in
CRAO
Cattle trucking appearance seen in
CRAO
Box carrying appearance seen in
CRAO
Disorders which we can see Cherry Red Spots
CHERRY TREES NEVER GROW TALL IN SAND AND GARDEN CRAO Trauma(blunt) Neimann pick disease Gangliosidosis Taysach disease Sandhaff’s disease Gaucher’s disease
Treatment of rhegmatogenous retinal detachment
Pars plana vitreostomy
+silicone oil in vitreous cavity
SF6/C3F8 (Gases)
Procedure called Pneumatic retinopaxy
Which is known as the Dangerous area of eye
Ciliary body
Sympathetic ophthalmitis occurs in
Non-traumatic eye
M/c presentation of ocular HIV
HIV Retinopathy
Earliest sign of ocular HIV
Cotton wool spots
MC asso. Tumorof ocular HIV
Kaposi Sarcoma
MC oppurtunistic infection of eye
CMV Retinitis
MC IO malignancy in children
Choroid melanoma
Origin and Insertion of EOMuscle
O: Common tendinous ring aka annulus of zinn
I: On sclera in front of equator at varying degrees
What enables binocular vision?
Simultaneous perception
Proper fusion
Stereopsis
Pizza pie appearance seen in
Ocular HIV
Collar stud appearance/ mushroom shape
CHOROID Melanoma
Vol. of eyeball
6ml
True basement membrane of eye
Internal limiting membrane of retina
Nerve supply of cornea
TON
Trigeminal
Ophthalmic
Nasociliary
Normal power of lens
16-190D
Near reflex is attained with the help of 3 components..what r dey??
Accomodation-Ciliary Muscle
Convergence-Medial Rectus
Miosis-Sphincter pupillae
Near reflex regulated by which nerve
3rd
Which side neuroretinal rim is broadest
Inferior
Diameter of Macula & optic disc
5.5 , 1.5 mm
Pigments of Macula lutea
Carotenoids
Lutein
Zeaxanthin
MCC of Bac.corneal ulcer in POST LASIK SURGERY
Atypical Mycobacterium
Bacteria which mimics fungal corneal ulcer
Nocardia
Which ulcer is caused by the 5th cranial nerve palsy
Neurotrophic/ Metaherpectic ulcer