Ondansetron Flashcards

1
Q

Drug Class of Ondansetron

A

Anti-emetic

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2
Q

Pharmacology of Ondansetron

A

Seretonin 5-HT3 antagonist

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3
Q

Metabolism of Ondansetron

A

By the liver and excreted via the kidneys

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4
Q

Indications of Ondansetron

A

Significant nausea and or vomiting

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5
Q

Contraindications of Ondansetron

A

Allergy/ ADR
Long QT syndrome
Current apomorphine therapy (used in parkinson’s disease)
Patients under 2

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6
Q

Precautions of Ondansetron

A
Hepatic impairment 
Pregnancy (first trimester)
Risk factors for Long QT syndrome 
Elderly patients 
Intestinal obstruction
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7
Q

Side effects of Ondansetron

A

Headache
Constipation
ECG changes

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8
Q

Presentation of Ondansetron

A

Amp, 4mg in 2ml

ODT

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9
Q

Onset, duration and half life of Ondansetron

A

5 minutes, several hours, 3-4 hours

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10
Q

Route of administration

A

PO, IM, IV

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11
Q

Adult dosage of Ondansetron

A

4-8mg Ondansetron.

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