Oncology Nursing Flashcards

1
Q

About how many women will develop cancer?

A

1/3

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2
Q

About how may men will develop cancer?

A

1/2

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3
Q

Cancer contributes to _/4 deaths.

A

1

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4
Q

Cancer ____ to heart disease as the most common cause of death.

A

2nd

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5
Q

Cancer will grow as long as it has ____ and _____.

A

nutrients and space

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6
Q

What is a cancer cell?

A

uncontrollable growth of irregular cells

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7
Q

Disorganized growth

A

dysplasia

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8
Q

increased cellularity

A

hyperplasia

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9
Q

abnormal appearing of cells

does not mean malignant

A

metaplasia

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10
Q

variance of size and shape of cell

A

pleomorphism

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11
Q

Good: has appearance of cell they originated from
Bad: Cannot tell where it came from (progressed cancers)

A

Differentiation

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12
Q

Cancer Cells:

A
  1. poor cell differentiation
  2. Invades other tissues
  3. Grow at new sites
  4. Avoid immune system
  5. Autonomy
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13
Q

Study of cancer

A

idiology

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14
Q

stops cells from proliferating

A

tumor suppressor genes

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15
Q

How do cancer cells get started?

A
  1. Exposure to carcinogens
  2. initiation
  3. promotion
  4. progression
  5. metastasis
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16
Q

Exposure to Carcinogens:

  1. incomplete-?
  2. complete-?
A

Incomplete- requires same cell to be exposed again after initiation.
Complete- directly causes the cancer

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17
Q

3 Stage Theory:

  1. initiation-?
  2. promotion-?
  3. progression-?
A
  1. Initiation- start with altered cell
  2. Promotion- enhances, alters, and lets it change
  3. Progression- neoplasm (new cell)
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18
Q

oncogene

A

controls for cancer cell

19
Q

proto oncogene

A

controls proliferation of a normal cell

20
Q

the grade of the cell = ?

A

the level of differentiation

21
Q

How do cancers grow?

A
  1. Reproducing cells

2. Doubling time

22
Q

Doubling time:

30 doublings = ?

23
Q

What is the earliest a cancer can be detected on an x-ray?

A

30 doublings (1 cm)

24
Q

How many doublings lead to death?

25
Cancer can also be detected by:
A change in blood counts
26
Cancer cells have to complete the cell cycle. | Do they have a restriction?
no
27
What is doubling time?
The time it takes for the cell to double in size
28
Is a tumor cell just one type of cell? | What is it called?
no | Tumor Heterogeneity
29
How do cancers metastasize? | 5 ways
1. Invasion of adjacent tissues 2. Enter blood and lymph vessels *** 3. Invasion/ evasion of immune system 4. Reentrance into distant tissue 5. Implantation of malignant cells in new tissue AKA seeding
30
when cancer cells break away from original tumor and are in blood cells
intravasation
31
certain tumor cells go to a certain distant site
homing
32
tumor creates its own blood supply
angiogenesis
33
Common Metastatic Sites of Primary Tumors:most to least | lung
liver, adrenal glands, bone, brain
34
Common Metastatic Sites of Primary Tumors:most to least | breast
lymph, bone, lung, liver
35
Common Metastatic Sites of Primary Tumors:most to least | stomach
liver
36
Common Metastatic Sites of Primary Tumors:most to least | anus
liver, lungs
37
Common Metastatic Sites of Primary Tumors:most to least | bladder
lungs, bone, liver
38
Common Metastatic Sites of Primary Tumors:most to least | prostate
bone, liver, lungs
39
Common Metastatic Sites of Primary Tumors:most to least | Uterine cervix
lungs, bone, liver
40
Common Metastatic Sites of Primary Tumors:most to least | colon
liver (direct hepatic drainage)
41
What are the three patterns of cancer occurrence?
1. Sporadic *** 2. Inherited 3. Familial cancer
42
certain cancers happen in families- not genetic | prone to that type of disease
familial cancer
43
a faulty repair gene | 5% of breast cancer
inherited