Oncology Meds Flashcards
What is 5-Fluorouracil (5-FU)?
An antimetabolite class of chemotherapy drugs that prevent the use of metabolites, interfering with normal cell division and function.
What are the side effects (S/E) of 5-Fluorouracil (5-FU)?
Diarrhea, bone marrow suppression, stomatitis, alopecia, tinnitus.
What is the antidote/protectant for 5-Fluorouracil (5-FU)?
Leucovorin (potentiator; methotrexate antidote).
What nursing interventions are needed for 5-Fluorouracil (5-FU)?
Patient education, monitoring for infection, sores in the mouth, and symptoms of allergic reactions.
What is Doxorubicin (Adriamycin) commonly referred to as?
“Red devil”.
What class of drug is Doxorubicin (Adriamycin)?
Antitumor antibiotic.
How does Doxorubicin (Adriamycin) treat cancer?
By affecting the genetic material within cancerous cells, preventing them from growing and spreading.
What is tissue necrosis?
Tissue necrosis refers to the death of cells or tissues in the body.
What are some side effects of certain medications?
Side effects include cardiac and pulmonary toxicity, alopecia, and bone marrow suppression.
What is a flare reaction?
A flare reaction is an increase in symptoms or a return of symptoms after treatment.
What does red urine in the first 48 hours of Doxorubicin indicate?
Red urine in the first 48 hours is a side effect.
What is the antidote/protectant for cardiac protection?
Dexrazoxane is used as an antidote/protectant to protect the heart.
What nursing interventions are important?
Nursing interventions include cardiac monitoring and educating about possible side effects like red urine.
What is Paclitaxel (Taxol)?
Paclitaxel (Taxol) is a medication used as an antimitotic (mitosis inhibitor).
What is the definition of antimitotic drugs?
Antimitotic drugs are those that stop cell division or mitosis by disrupting microtubules.
What are the side effects of antimitotic drugs?
Side effects include bone marrow suppression, fever without infection, and alopecia.
What nursing interventions are needed for vital signs?
Vital signs should be monitored, especially with a history of cardiac issues.
What premedication is recommended?
Premedication with Benadryl is recommended.
What is Dexamethasone?
A medication used in various conditions, including inflammation and autoimmune diseases.
What is Ranitidine?
A medication that reduces stomach acid production.
What is Vincristine (Oncovin)?
An antimitotic (mitosis inhibitor) medication.
What are the side effects of Vincristine?
Alopecia, neurotoxicity (numbness, loss of feelings), phlebitis, and mild bone marrow suppression.
What is hyperuricemia?
An elevated level of uric acid in the blood.
What is the antidote for hyperuricemia?
Allopurinol.
