oncology markers and translocations

Question 1

CD15 CD30

Answer 1

redd sternberg

hodgkins except nodular sclerosing (lacunar)

Question 2

t(8;14)

Answer 2

Burkitts lymphoma

c=myc and heavy chain ig

Question 3

t(14;18)

Answer 3

follicular lymphoma

bcl2 and heavy chain Ig

Question 4

t(11;14)

Answer 4

mantle cell lymphoma

cyclin D1 and heavy chain Ig

Question 5

CD5+ lymphoma

Answer 5

mantle cell

Question 6

cerebriform nuclei CD4+

Answer 6

mycosis gungoides with sezary shdrome

Question 7

increased IgA and IgG with CRAB

Answer 7

multiple myeloma

Question 8

increased IgM with no CRAB

Answer 8

waldernstrom

Question 9

bilobed PMN

Answer 9

pseudo pelger huet anomal after chemothearpy

Question 10

Tdt CD10

Answer 10

pre b cell AML

Question 11

tdt

Answer 11

pre T cell AMl

Question 12

TRAP

Answer 12

haity cell

cyclin d1

Question 13

CD20 CD15

Answer 13

CML

Question 14

t)15;17)

Answer 14

M3 AML

give trans retinoic acid

Question 15

dic

Answer 15

AML

Question 16

t(9;22)

Answer 16

CML bcr abl treat witm imatinip

Question 17

low LPA with lots of lymophocytes in blood

Answer 17

CML

Question 18

t(12;21)

Answer 18

good prognosis for ALL

Question 19

S100

CD1a

Answer 19

langerhand cell histocytosis

Question 20

birbeck granules

Answer 20

langerhans cell histocytosis

Question 21

teardrop

Answer 21

myelofibrosis

Question 22

icnreased plasma volume
low EPO
increased red blood cell mass

Answer 22

poycythemia vera