Oncology Flashcards
Why could lung cancer cause voice hoarseness?
Invasion of recurrent laryngeal nerve paralyses vocal cords
Clinical presentation of lung cancer
Haemoptysis
Recurrent pneumonia
Volume loss
Stridor
If a tumour invades the brachial plexus it is known as what? What is the sequence of events leading to this?
Pancoast tumour
Erodes through ribs
T1 root invasion
Where are common sites of metastasis?
Brain Liver Bone Adrenal gland Skin
What are the paraneoplastic effects of lung cancer?
Clubbing Hypertrophic pulmonary osteoarthropathy - Periosteum elevates from bone Weight loss Thrombophlebitis Hyper calcareous Hyponatraemia
PTH secreting lung tumour
Squamous cell carcinoma
ACTH secreting lung tumour
Small cell Cancer
Types of lung cancer?
Small cell carcinoma Non-small cell - Adenocarcinoma - Squamous cell carcinoma - Large cell carcinoma
Which type is most chemosensitive?
Small cell carcinoma
Where are adenocarcinomas typically situated; centrally or peripherally?
Peripherally
What is a carcinoid tumour?
Neuroendocrine neoplasm of low grade malignancy
How can cancers be staged? (Investigations)
Bronchoscopy Mediastinotomy Brain CT Thorax CT PET scan