Interstitial And Occupational Lund Disease Flashcards
What is sarcoidosis?
Granulomatous (Type iv) disease
What symptoms does interstitial lung disease cause?
SoB
Dry cough
Symptoms of acute sarcoidosis?
Erythema nodosum Bilateral hilar lymphadenopathy Arthritis Uveitis Fever
Symptoms of chronic sarcoidosis?
Lung infiltrates
Skin infiltrates
Peripheral lymphadenopathy
Hypercalcaemia
What investigations would be carried out to diagnose sarcoidosis?
CXR and CT
Tissue biopsy
ACE level check (high in sarcoidosis)
Treatment of sarcoidosis
Immunosuppression
- Azathioprine
- Methotrexate
- Anti-TNF therapy
What is extrinsic allergic alveolitis?
Type iii hypersensitivity
What causes extrinsic allergic alveolitis?
Thermopilic bacteria - Farmers/Malt workers/Mushroom workers lung Avian antigens - Bird fanciers lung Drugs - Gold - Bleomycin/Methotrexate
Symptoms of extrinsic allergic alveolitis
Cough SoB Fever Myalgia Several hours after exposure Crackles Hypoxia
How does extrinsic allergic alveolitis appear on CXR?
Widespread infiltrates
Ground-glass appearance on CT
Idiopathic pulmonary fibrosis
A benign condition caused by asbestos exposure
Pleural plaques
Malignant condition caused by asbestos
Mesothelioma
What kinds of biopsy can be performed in ILD?
Transbronchial
Thoracoscopic