Oncology 2- Paulson (Child Cancers)

Question 1

A 2-5 year old presents with LAD, HSM and fever. What type of cancer are these symptoms indicative of?

Answer 1

Acute lymphocytic leukemia

Question 2

Anemia, thrombocytopenia and blasts are noted on peripheral smear of this type of CA?

Answer 2

Acute lymphocytic leukemia

Question 3

What confirms the dx of Acute lymphocytic leukemia (ALL)?

Answer 3

Bone marrow

Question 4

Treatment of choice for Acute lymphocytic leukemia?

Answer 4

Chemo

Question 5

This child presents with an early morning HA relieved by N/V and also macrocephaly (overly large head). What type of tumor might this child have?

Answer 5

CNS tumor

Question 6

To diagnose a CNS tumor what should we do?

Answer 6

MRI and bx

Question 7

What is the treatment for CNS tumor?

Answer 7

Open surgical repair for dx and remove most of the tumor

Question 8

What CNS tumor treatment should we avoid in kids less than 3 years old?

Answer 8

XRT

Question 9

An infant and her mom present to the office because the mom was taking a photo of her baby and noticed a white pupil on the picture. After talking to the mom, you find out the mom has the RB1 gene. What should you do?

Answer 9

Refer to optho

Question 10

You get an Xray handed to you that shows a Codman triangle and also another that shows a spiculated “sunburst appearance.” What are you concerned about for this patient?

Answer 10

Osteosarcoma

Question 11

Kids with this type of cancer may also have localized pain and Paget disease.

Answer 11

Osteosarcoma

Question 12

A male patient presents to your office with bone pain and swelling that started a few months ago. Upon further questioning, the patient tells you the pain is worse at night and with exercising. What might this be indicative of?

Answer 12

Ewing Sarcoma

Question 13

Small round blue cell tumor

Answer 13

Ewing Sarcoma

Question 14

Ewing Sarcoma is mc found in the ________ & ________

Answer 14

long bones & pelvis

Question 15

To diagnose a patient with Ewing Sarcoma you get a _______. It would show “onion peel” periosteal reaction and often “moth-eaten” or “permeative” destructive lesion

Answer 15

xray

Question 16

How do you treat Ewing Sarcoma?

Answer 16

Chemo then local control with surgery and XRT

Question 17

An African American child presents to your office with a nontender unilateral abdominal mass. What is the first imagining study you would perform and how is the dx confirmed? Oh, what is the dx also?

Answer 17

Abdominal u/s & bx

Wilms Tumor AKA Nephroblastoma

Question 18

What is the treatment for Wilms Tumor AKA Nephroblastoma

Answer 18

Surgical resection & chemo