Oncology Flashcards
1
Q
What are the main side effects of eGFR targeted tyrosine kinase inhibitors eg osimertinib?
A
- N&V
- Acneiform rash 2-4 weeks after starting
- Ocular side effects
- LFT derangement -> hepatotoxicity
- Cardiac - QTc prolongation, reduced LVEF
- Late toxicity - Interstitial Lung disease
Cost - $7000/month
