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Finals > Oncology > Flashcards

Oncology Flashcards

1
Q

What are the cancer screening principles?

A
  • must be an important health problem
  • latent or early symptomatic stage
  • natural history, development from latent to declared disease, adequately understood
  • test must be suitable with a high level of accuracy
  • test acceptable to the population
  • accepted treatment
  • facilities for the diagnosis and treatment
  • agreed policy who to treat
  • cost should be economically balanced in relation to possible expenditure on medical care
  • continuing process, not a once and for all
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2
Q

What is the immediate management of SVC obstruction?

A
  • Dexamethasone 8mg BD
  • PPI cover
  • oxygen
  • LMWH
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3
Q

What is the definitive management of SVC obstruction?

A
  • stent
  • radiotherapy
  • chemotherapy
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4
Q

What is the mangement of VTE in cancer?

A
  • D dimer is not useful as raised anyway
  • DOAC (apixaban)
  • LMWH
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5
Q

What are the issues with a doac in cancer?

A
  • can interact with chemo
  • higher risk of GI bleed
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6
Q

When should you think of neutropenic sepsis?

A
  • Recent chemo with any of: Fever >38, hypothermia<36, chills, shivers, sweats, any indication of infection
  • SIRS/sepsis with neutropenia <1/0.5
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7
Q

What is the management of neutropenic sepsis?

A
  • sepsis 6
  • broad spectrum antibiotics within 1 hour of presentation
  • screen for source
  • monitor FBC daily
  • IV piperacillin/tazobactam 4.5g 6 hourly
    • van IV if MRSA suspected
    • IV gent if NEWS≥7 or less than 7 but currently chemo or stem cell transplant
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8
Q

What is the tissue diagnosis for brain mets?

A
  • Neurosurgery
  • EBUS+ FNA
  • CT guided biopsy
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9
Q

What is the immediate management of brain mets?

A
  • Dexamethasone 8mg BD
  • PPI
  • Advise not to drive
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10
Q

What is the definitive management of brain mets?

A
  • Surgery
  • radiotherapy
  • chemotherapy
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11
Q

What cancers are the most likely cause of brain mets?

A
  • lung
  • renal cell
  • breast
  • melanoma
  • GI cancer
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12
Q

What are the symptoms of brain mets?

A
  • ICP symptoms
  • neurological deficit
  • seizure
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13
Q

What is the management of an obstructive hydrocephalus?

A

shunt

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14
Q

Titration of steroid in the context of cancer

A
  • 25% every 3 days
  • maintenance dose of 2-4mg OD if required
  • If seizure then add levetiracetam
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15
Q

What are the most common causes of bone mets?

A
  • breast cancer
  • prostate
  • lung
  • myeloma
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16
Q

Immediate management of malignant spinal cord compression

A
  • MRI whole spine
  • Dexamethasone 8mg BD
  • PPI protection
  • analgesia
  • laxative
  • contact oncolgy on call
17
Q

What is the definitive management of spinal cord compression

A
  • surgery
  • radiotherapy
  • chemotherapy

Finals (37 decks)

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