Emergency medicine Flashcards
Airway signs of anaphylaxis
Swelling of the throat -> stridor and hoarse voice
Breathing signs of anaphylaxis
Respiratory wheeze, dyspnoea
Circulation signs of anaphylaxis
Tachycardia, hypotension
Adrenaline for anaphylaxis under 6 months
100-150 micrograms (0.1-0.15ml 1 in 1000)
Adrenaline for anaphylaxis 6 months to 6 years
150 micrograms (0.15ml 1 in 1000)
Adrenaline for anaphylaxis 6-12 years
300 micrograms (0.3 ml 1 in 1000)
Adrenaline for anaphylaxis over age 12
500 micrograms (0.5ml 1 in 1000)
After how many minutes can you repeat adrenaline in anaphylaxis?
5 minutes
Site IM adrenaline injection
Anterolateral aspect of middle third of the thigh
What is refractory anaphylaxis?
Respiratory or cardiovascular problems despite two doses of IM adrenaline
Management of refractory anaphylaxis
- IV fluids for shock
- consideration of IV adrenaline infusion
Management of anaphylaxis after stabilisation
- non sedating anti-histamines if continuing skin rash/urticaria
- serum tryptase to see if anaphylaxis
- if new episode of anaphylaxis refer to specialist allergy clinic
- prescribe and show patient how to use 2 adrenaline auto injectors
- WHO risk stratified approach to discharge
Who can be discharged after 2 hours from anaphylaxis?
- good response to a single dose of adrenaline
- complete resolution of symptoms
- given adrenaline auto-injector and trained how to use it
- adequate supervision following dishcarge
Discharge 6 hours after anaphylaxis
- 2 doses of IM adrenaline required
- or previous biphasic reaction
Discharge minimum of 12 hours from anaphylaxis
- severe reaction requiring >2 doses of IM adrenaline
- possibility of ongoing reaction e.g. modified slow release
- severe asthma
- difficult access to emergency care
- late at night
Rate of compressions to ventilation in an adult
30:2
What are the shockable rhythms?
- pulseless VT
- ventricular fibrillation
What are the non shockable rhythms
- asystole
- PEA
Shocks in a witnessed cardiac arrest of a monitored patient
stacked shocks: 3 successive quick shocks
Drugs in cardiac arrest for a non shockable rhythm
- give adrenaline 1mg as soon as possible
- repeat every 3-5 minutes
Drugs in cardiac arrest for a shockable rhythm
- give adrenaline 1mg after third shock
- give amiodarone 300mg after 3 shocks then 150mg after 5 shocks
When should thrombolytic drugs be given in the context of cardiac arrest
if pulmonary embolus is suspected
If thrombolytic drugs are given in cardiac arrest, how long should cpr be continued for?
60-90 minutes
Reversible causes of cardiac arrest
4H’s:
- hypoxia
- hyperkalaemia
- hypothermia
- hypovolaemia
4T’s:
- toxins
- thrombus
- tamponade
- tension pneumothorax
Definition of sepsis
life-threatening organ dysfunction caused by a dysregulated host response to infection
qSOFA score
- resp rate >22
- Altered mentation
- systolic BP <100mmHg
Heightened risk of mortality if score 2 or higher
Sepsis 6
- IV antibiotics
- oxygen
- IV fluids (fluid challenge)
- serum lactate
- blood cultures
- urine output
6 types of shock
- haemorrhagic
- septic
- cardiogenic
- neurogenic
- anaphylactic
- hypovolaemic
What is neurogenic shock?
Tends to occur in patients who have a transected spinal cord interrupting the autonomic nervous system resulting in decreased sympathetic tone or increased parasympathetic tone
What is status epilepticus?
- single seizure lasting over 5 minutes
- 2 seizures within 5 minutes, without the person returning to normal in between them
Management of status epilepticus
- ABC: airway adjunct, oxygen, check blood glucose
- PR diazapam or buccal midazolam if not in hospital
- IV lorazepam if in hospital, can be repeated after 5-10 minutes
- If ongoing give levetiricetam
- if no resolution after 45 minutes then consider general anaesthesia or phenobarbital
Pre renal causes of AKI
- hypovolaemia
- renal artery stenosis
Renal causes of AKI
- glomerulonephritis
- Acute tubular necrosis
- acute interstitial necrosis
- rhabdomyolysis
- tumour lysis syndrome
Post renal causes of AKI
- kidney stone in ureter or bladder
- BPH
- external compression of the ureter
Nephrotoxic drugs
- NAIDs
- aminoglycosides
- ACEi
- ARB
- diuretics
Definition of AKI
- <0.5ml per kg per hour urine output
- rise in creatinine of 26mmol in the past 48 hours
- 50% or greater rise in serum creatinine over the past 7 days
Which drugs may have to be stopped in AKI because of risk of toxicity
- metformin
- lithium
- digoxin