Oncogenic Viruses Flashcards
HPV causes which three cancers?
Genital tumors
Squamous Cell Carcinoma
Oropharyngeal carcinoma
EBV causes what 4 cancers?
Burkitt Lymphoma
Nasopharyngeal Carcinoma
Hodgkin Disease
B cell lymphoma
HHV-8 causes which neoplasm?
Kaposi sarcoma
Hep B/Hep C lead to which neoplasm?
Hepatocellular carcinoma
HTLV causes which neoplasm?
Adult T Cell Lymphoma
Which are the most common virus-associated cancers seen in men vs women?
Men: Liver
Women: Cervical
Is HPV enveloped or naked?
Naked –> very stable
What do E6 and E7 inhibit?
E6 –> p53
E7 –> Rb
Podophyllotoxin cream, Imiquimod cream and Cidofovir can all be used to treat what?
HPV warts
Is guardasil effective if the patient already has CIN?
No
Why should men be vaccinated against HPV?
Head and neck cancers