Oncogenes Flashcards

1
Q

BCR-ABL

A

CML, ALL

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2
Q

BCL-2

A

follicular lymphoma

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3
Q

BRAF

A

melanoma

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4
Q

c-kit

A

Gastrointestinal stromal tumor

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5
Q

c-myc

A

Burkitt lymphoma

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6
Q

Her2/neu (c-erbB2)

A

Breast

Ovarian, gastric

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7
Q

L-myc

A

Lung tumor

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8
Q

N-Myc

A

Neuroblastoma

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9
Q

RAS

A

colon cancer, lung, pancreatic cancer (a lot of cancers)

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10
Q

RET

A

MEN 2A and 2B,

medullary thyroid cancer

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11
Q

CCND1

cyclin d

A

Mantle cell lymphoma

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12
Q

PDGF-beta

A

Astrocytoma, osteogenic sarcoma

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