ONCO-2 Flashcards

1
Q

benign; slow-growing but locally invasive and persistent; does not metastasize

A

Ameloblastoma (Epithelial Tumor)
Description

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2
Q

typically form rounded & cyst - like radiolucency with moderately well-defined
margins and appear as multilocular - “soap bubble” or honeycomb appearance

A

Ameloblastoma (Epithelial Tumor)
Radiographic Feature

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2
Q

common to all subtypes is the palisading (fence-like) of columnar cells around
epithelial nests in a pattern similar to that of ameloblasts of enamel

A

Ameloblastoma (Epithelial Tumor)
Histopathology

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2
Q

The amyloid materials present characteristics annular (ringlike) staining pattern, called Liesegang rings

A

Calcifying Epithelial Odontogenic Tumor (CEOT)
Histopathology

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2
Q

presence of a radiopaque mass in the center of the lesion (black arrow) with radiopaque streaks has the appearance of
“driven snow” scattered flecks of calcification

A

Calcifying Epithelial Odontogenic Tumor (CEOT)
Radiographic

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3
Q

divergence of roots and displacement of teeth occurs more frequently than root resorption

A

Adenomatoid Odontogenic Tumor (AOT)
Radiographic

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4
Q

Rosettes and ductlike structure of columnar
epithelial cells surrounding small foci of calcification

A

Adenomatoid Odontogenic Tumor (AOT)
Histopathology

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5
Q

It forms cavity that is filled with semi solid or semi liquid substance a combination of cyst in a neoplastic growth

A

Odontogenic Keratocyst (OKC) or Keratocyst
Odontogenic Tumor
Description

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6
Q

The lining presents stratified squamous
epithelium with a parakeratinized surface

A

Odontogenic Keratocyst (OKC) or Keratocyst
Odontogenic Tumor
Histopathology

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7
Q

Made of fibrous connective tissue stroma scattered with islands of clear cells

A

Clear Cell Odontogenic Tumor (Carcinoma)
Histopathology

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8
Q

● Honeycomb - Multilocular (small)
● Tennis Racket - Triangular
● Soap Bubble - Big rounded

A

Odontogenic Myxoma
Radiographic Features

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9
Q

Fibroblast ( Spindle-shaped cells),stellate-shaped cells, and collagen fibers scattered in a mucoid substance

It has soft gelatinous consistency

A

Odontogenic Myxoma
Histopathology

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10
Q

Mucoid, Mucoid intercellular substance which contains scattered fibroublast (spindle shape) , Stellate shape cells
and Collagen Fibers (mucous tissue)

A

Odontogenic Myxoma

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11
Q

Purely radiolucent with well defined margins because of pure soft tissue tumor
containing small globules or islands of calcified deposit

A

Central Odontogenic Fibroma
Radiographic

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12
Q

Late stage - calcified deposit may be present (dentin or cementum)

A

Central Odontogenic Fibroma
Histopathology

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13
Q

(Early Stage)
- Well defined radiolucency with sclerotic margin ( in histopath you can see cementoblast and osteoblast )

(Middle Stage)
- Globules or calcified deposit would appear as spots and radiopaque structure

A

Cementifying Fibroma Ossifying Fibroma
Radiographic

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14
Q

Tumor that arises in cementoblast

A

Cementoblastoma (True Cementoma)
Description

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15
Q

Reactive lesion rather than neoplastic growth

Unusually responds to unknown factor

A

Periapical Cemento-Osseous Dysplasia
Description

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16
Q

Calcified deposits:
Trabeculae, Ovoid, Spicules or irregular masses

A

Periapical Cemento-Osseous Dysplasia
Histopathology

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17
Q

Tennis racket

A

Odontogenic Myxoma

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18
Q

Signs and Symptoms:
● slow clinical growth and does not tend to infiltrate between trabeculae of bone;

A

Ameloblastic FIbroma (Mixed Tumor)
Clinical Features

19
Q

well circumscribed and usually are surrounded by a sclerotic margin

A

Ameloblastic FIbroma (Mixed Tumor)
Radiographic Features

20
Q

because of tumor encapsulation and the
general lack of invasive capacity, this lesion is treated through a conservative surgical
procedure such as curettage or excision.

A

Ameloblastic FIbroma (Mixed Tumor)
Treatment

21
Q

Are the benign tumors, which may occur anywhere in the body

22
A form of heterotropia, are masses of normal tissues found in abnormal locations.
Choristomas
23
a tumor made up of several different types of tissue, such as hair, muscle, or bone.
Teratomas
24
Radiolucent, Opaque-Lucent, Multiocular Well circumscribed, well defined margin
Juvenile Ossifying Fibroma Radiographic Features
25
Storiform whord pattern
Juvenile Ossifying Fibroma Histopathology
26
made out of Bony spheroids because it is rounded islands of bone or bony trabeculae
Juvenille ssifying Fibroma
27
They produce excess fibers Appear as irregular shape island describe as chinese character appearance pattern or bony trabeculae
Fibrous Dysplasia Histopathology
28
Ground glass opacity “GGO” Orange peel radiopacity - honeycomb, multilocular Mottled appearance Elliptical in shape - oval or egg shape Poorly defined margins - continues, no clear boundary to the bone
Fibrous Dysplasia Radiographic
29
More than 3mm diameter
Osteoblastoma
30
Less than 3 mm Distinct radiographic appearance presents as central zone as “nidus”
Osteoid Osteoma
31
Less than 3mm Composed of central zone called “nidus”
Osteoid Osteoma Radiographic
32
Layers of lamellar trabeculae of cancellous bone with abundant fibro-fatty marrow Dense compact bone with few bone marrow
Osteoid Osteoma Histopathology
33
Well-defined lobules of mature hyaline cartilage Similar to osteoma instead of a dense mass of compact bone, it is a large lobules Matured hyaline cartilage that has gone abnormal formation forming chondroma
Chondroma Histopathology
34
Excess proliferation of abnormal cells (osteoblast, large cells containing nucleus)
Central Giant Cell Granuloma
35
Numerous osteoclast-like cells, multinucleated giant cells, and fibroblasts in well-vascularized connective tissue stroma Large cells containing large nucleus
Central Giant Cell Granuloma Histopathology
36
Unilocular or multilocular radiolucency with well-demarcated,scalloped border
Central Giant Cell Granuloma Radiographic
37
Purely blood vessels
Hemangioma
38
KIDNEY SHAPE
Langerhan Cell Disease
39
Excess stroma/bone
Tori and Exostoses
40
Associated with pagets disease were in the coronoid process continually enlarge or grow
Coronoid Hyperplasia
41
Prone to develop paget's disease
Osteosarcoma
42
Ill-defined border
Osteosarcoma Radiographic Features
43
globules of malignant cartilage
Chondrosarcoma
43
Supporting stroma typical fibroblast or spindle shape cells Parenchyma Most bony trabeculae network is made of osteoid/woven bone(immature bone)
Osteosarcoma Histopathology
44
atypical small round cells it is light and dark cells
Erwing’s Sarcoma
45
It presents characteristics such as starry-sky pattern
Burkitt's lymphoma
46
bone marrow - formation of diff blood cells Bone marrow continuously produce abnormal plasma cell
Multiple Myeloma
47
there is increase production of protein even the urine would present positive to protein
Multiple Myeloma Clinical Features