Onc/Pall Flashcards
For which cancer is calcitonin a tumour marker?
Medullary thyroid cancer
Bones have medulla and are made of calcium = Medullary thyroid cancer + Calcitonin
How is buprenorphine metabolised?
By the liver - suitable as an alternative to oxycodone in renal impairment
BRCA2 mutation is associated with which cancer in men
Prostate
How do we convert oral to sc morphine?
Divide by two for oral to subcutaneous morphine conversion
Where would you see an elevated ca 19-9?
Pancreatic cancer
How do we treat hiccups in palliative care?
Hiccups in palliative care - chlorpromazine or haloperidol
Where would you see a raised alpha-feto protein?
Liver cancer
What is midazolam?
Midazolam is a short-acting benzodiazepine that provides sedation, anxiolysis, and amnesia.
What cytotoxic agent can cause lung fibrosis?
Bleomycin
What cytotoxic agent can cause haemorrhagic cystitis?
Cyclophosphamide
What cytotoxic agent can cause hypomagnesemia?
Cisplatin
What cytotoxic agent can cause peripheral neuropathy?
Vincristine
What cytotoxic agent can cause Myelosuppression, liver fibrosis and oral mucositis?
Methotrexate
What cytotoxic agent can cause cardiomyopathy?
Doxorubicin
A 65-year-old female with metastatic breast cancer is reviewed in clinic. Her husband reports that she is increasingly confused and occasionally appears to talk to relatives that are not in the room. She undergoes investigations for reversible causes, of which none are found. If conservative measures fail and she continues to be confused/agitated, what is the most appropriate management?
Haloperidol
Midazolam if end of life
