Olmsted stndrome Flashcards
1
Q
Mutation in
A
TRPV3
2
Q
characterized by
A
Mutilating palmoplantar kerstoderma and periorificial keratotic plaques. distinctive features are sharply marginated palmoplantar keratoderma, constrictiin of digits, linear keratotic streaks on flexural aspects of wrists, onychodystrophy and periorificial keratoses. constriction of digits result to spont amputation.
3
Q
histo
A
Acanthoses
papillomatoses
orthokeratotic hyperkeratosis.
OLM- APO
4
Q
what does Ki-67 staining of suprabadal keratinocytes suggest?
A
Olmsted syndrome is a hyperproliferative disorder of the epidermis.
