olfaction Flashcards

1
Q

sensory receptors are found on the

A

olfactory epithelium

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2
Q

threshold varies with different molecules

A

ethanol 2mM

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3
Q

interpretation of smell is conc dependent

A

indole

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4
Q

olfaction is a reflection of the

A

pattern of different cells that are activated by the different molecules

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5
Q

pheromones

vomeronasol organ expresses a specific subset of molecules called

A

vomeronasal receptors

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6
Q

pheromones

accessory olfactory bulb

A

prjoects to the amygdala and hypothalamus

regulates behaviour and mood

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7
Q

olfactory neurons are

A

bipolar

and unmyelinated

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8
Q

where are they embedded

A

mucus layer

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9
Q

mucus layer is projected by

A

bowmans capsule

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10
Q

what does the mucus layer provide

A

concentrates the chemicals at the apical

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11
Q

how long do the neurons last

A

6-8 weeks

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12
Q

what type of receptor is used

A

GPCR

large amount of sequence variability

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13
Q

once alpha is released what happens

A

activates adenylate cyclase 3
atp—- cAMP
which activates CNG allowing Na+ and Ca2+ in

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14
Q

after AP the axon passes through what

A

cribriform plate to the olfactory bulb

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15
Q

glomeruli what happens

A

same odorant receptor projects to the same region

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16
Q

the relationship between 1 type of olfactory neuron and 1 glomeruli enables specific regions of the bulb to

A

respond selectively to different chemicals

17
Q

different chemicals will activate a

A

unique spatial pattern in the bulb

18
Q

a single glomerulus can contain

A

dendrites from upto 25 mitral cells increasing amplification