olfaction Flashcards
sensory receptors are found on the
olfactory epithelium
threshold varies with different molecules
ethanol 2mM
interpretation of smell is conc dependent
indole
olfaction is a reflection of the
pattern of different cells that are activated by the different molecules
pheromones
vomeronasol organ expresses a specific subset of molecules called
vomeronasal receptors
pheromones
accessory olfactory bulb
prjoects to the amygdala and hypothalamus
regulates behaviour and mood
olfactory neurons are
bipolar
and unmyelinated
where are they embedded
mucus layer
mucus layer is projected by
bowmans capsule
what does the mucus layer provide
concentrates the chemicals at the apical
how long do the neurons last
6-8 weeks
what type of receptor is used
GPCR
large amount of sequence variability
once alpha is released what happens
activates adenylate cyclase 3
atp—- cAMP
which activates CNG allowing Na+ and Ca2+ in
after AP the axon passes through what
cribriform plate to the olfactory bulb
glomeruli what happens
same odorant receptor projects to the same region