olfaction Flashcards

chapter 14

1
Q

odor

A

any smell sensation

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2
Q

odorant

A

a chemical compound that we can smell
- it must be volatile, small and hydrophobic

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3
Q

nose function

A
  1. filter and hummidify air
  2. smell
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4
Q

olfactory cleft

A

part at the back of the nose where the main olfactory epithelium is located

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5
Q

olfactory epithelium

A

patch of tissue in the upper nose that contains ORNs and is covered in a layer of mucus

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6
Q

cribiform plate

A

a bony tructure riddled with tiny holes that separates the nose from the brain
- axons of the ORNs pass through it

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7
Q

anosmia

A

the total inability to smell often resulting from illness or head injuries
- loss of taste

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8
Q

supporting cells

A

metabolic and physcial support to the olfactory receptors

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8
Q

cells in the olfactory epithelium

A
  1. supporting cells
  2. basal cells
  3. olfactory receptor neurons
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8
Q

basal cells

A

precursor cells to olfactory receptor neurons
- help replace them when they die

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9
Q

olfactory receptor neurons

A

the main cell type that contains receptors on its ilia
- located under the watery mucous layer

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10
Q

olfactory bulb

A

bulbous end of the olfactory tract containing mitral, tufted and glomeruli cells

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11
Q

mitral cells

A

the main projective output neurons in the olfactory bulbs
- relay

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12
Q

tufted cells

A

sencodary output neurons in the olfactory bulbs
- their axons form the olfactory tract which go to the brain

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13
Q

glomeruli

A

spherical conglomerates containing the incoming axons of the ORNS
- each receptor cells converge onto two glomureli and then synapse onto the mitral and tufted cells

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14
Q

cilia

A

hair like prootrusions on the dendrites of ORNs that contain receptors for oderants

15
Q

olfactory receptors

A

region on the cilia that oderant molecules bind to

16
Q

ORN adaptation

A

the nose adapts to oderants so if ypu give a burst then another immediately after, they will respond less to the second one
- if you wait 5 seconds it will be recovered
- cortical adaptations happens too

17
Q

psuedogenes

A

we have about 1000 different genes but about 60-70% dont work.
- so we have about 300-400 receptors

18
Q

neural coding for odors

A

the receptors each bind to one specific molecule but they work together in a population code to to account for the whole variety of smells we perceive

19
Q

piriform cortex

A

the primary olfactory cortex which receives signals directly from the olfactory bulb
- dedicated solely to olfaction

20
Q

entorhinal cortex

A

receives direct input from olfactory regions and provides the major association input into the hippocampus

21
Q

amygdala-hippocampus complex

A

critical for the unique emotional associative properties of olfactory cognition

22
Q

limbic system

A

the encompassing group of neural structures that include the olfactory cortex, amygdala, hippocampus, piriform cortex and entorhinal cortex
- olfaction is very connected to this system which gives it unique emotional associations

23
Q

tip of the nose phenomenon

A
  • when you know a smell but cat name it
  • olfaxtion is disconnected from language and does not fo through the thalamus so it does not integrate with the other senses
24
Q

cross adaptation of smell

A

the reduction in detection of an oderant following exposure to another oderant

25
Q

cognitive habituation

A

psychologucal process by which, after a long term exposure to an odorant, one is no longer able to detect that odorant or has very diminished ability

26
Q

why do we have cognitive habituation of smell

A
  1. receptors may be hindered after continuous exposure and may take longer to recycle
  2. odorant molecules may be absorbed into bloodstream
  3. cognitive-emotional factors
27
Q

attention and smell

A

we need some level of attention to smell
- looking for smell helps us detect it