Old Exam I Flashcards
Dendrotoxin
Blocks VR K channels
Dystrophin
DMD - muscular dystrophy
Phospolipase A2 aactivation
Ultimately leads to leukotriene production
DHP receptors are
Present in the sarcolemma
When relaxed, a sarcomere’s band
Gets wider
Neostigmine
Inhibits ACHase, Counteracts effects of curare (and anesthesia!)
Hyperpolarization is due to
Efflux of K
APs involve ____ channels, GPs involve ____ channels
Voltage gated, chemical gated
T/F, skeletal muscles have gap junctions?
False! This is smooth muscle.
Neural temporal summation is when
neuron releases lots of neural transmitters at a time (frequency increases!)
IP3 does what?
Causes Ca to be released from ER
Threshold potential is determined by
The voltage that VR Na channels open
Absolute refractory period is when what are inactivated?
VR Na channels
A sub threshold stimulus delivered to a neuron
Results in a graded potential, causes chemically regulated channels to open, but not voltage regulated
Muscle fibers are a collection of
myofibrils
Myofibrils are a collection of
Actin and myosin
Muscle fascicles are a collection of
Muscle cells
Oxygen debt refers to
Reclaiming ATP from excess lactic acid
Oxygen debt refers to
Reclaiming ATP from excess lactic acid
Smooth muscle cells contract by
Having Ca - calmodulin complex activated by MYOSIN KINASE cascade
Myoglobin
Allows muscle fibers to remain aerobic even when blood cannot bring O2
Latency in a twitch is due to the time it takes
An AP to be generated and travel along sarcolemma, VR Ca channels located in T-tubule to open
(Graph in which stimulus increases with frequency)
Recruitment
Curare
CR Channel blocker
