Olanzapine/ Zyprexa Flashcards
0
Q
Mech of action
A
SSRI, NE Reuptake inhibitor > antipsychotic and anticholinergic effects
1
Q
Classification
A
Antipsychotic
2
Q
Pharmacokinetics
A
OOA- <30min
Peak- 6hrs
Duration- Varies
Half life- 21-54hrs
3
Q
Indications
A
Acute psychosis or agitation
Alzheimer’s disease
4
Q
Contraindications
A
Hypersensitivity
5
Q
Side effects
A
Myalgia, somnolence, dizziness, tremor, tachycardia, postural hypotension, nausea, dry mouth
6
Q
Dose
A
Adult- 10mg IM
Pedi- N/A
7
Q
Precautions
A
Caution pt with CV disease, predisposition for hypotension, and parkinson’s diseases
Must be re-constituted in 3ml sterile water prior to admin
8
Q
Drug-Drug
A
Potentiates hypotensive effects of antihypertensives