Olanzapine/ Zyprexa Flashcards

0
Q

Mech of action

A

SSRI, NE Reuptake inhibitor > antipsychotic and anticholinergic effects

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1
Q

Classification

A

Antipsychotic

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2
Q

Pharmacokinetics

A

OOA- <30min
Peak- 6hrs
Duration- Varies
Half life- 21-54hrs

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3
Q

Indications

A

Acute psychosis or agitation

Alzheimer’s disease

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4
Q

Contraindications

A

Hypersensitivity

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5
Q

Side effects

A

Myalgia, somnolence, dizziness, tremor, tachycardia, postural hypotension, nausea, dry mouth

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6
Q

Dose

A

Adult- 10mg IM

Pedi- N/A

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7
Q

Precautions

A

Caution pt with CV disease, predisposition for hypotension, and parkinson’s diseases
Must be re-constituted in 3ml sterile water prior to admin

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8
Q

Drug-Drug

A

Potentiates hypotensive effects of antihypertensives

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