Oesophagus Physiology Flashcards

1
Q

First phase of swallowing

A

Oral = Voluntary

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2
Q

Second phase of swallowing

A

Pharyngeal = involuntary

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3
Q

Third phase of swallowing

A

Oesophageal = involuntary

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4
Q

Oral Phase two sub-phases

A

Preparatory = Mastication, mechanical digestion -> bolus

Transfer = Bolus propelled into pharynx

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5
Q

Physiological change during oral phase

A

Tounge closes off anterior oral cavity = bolus pushed to back of mouth

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6
Q

Physiological change during pharyngeal phase

A

Bolus peristalsised down the pharynx

Soft palate elevates = seals upper airway

Epiglottis swings down = seals lower airway

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7
Q

Oesophageal Phase

A

Upper oesophageal sphinchgter relaxes = bolus in oesophagus

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8
Q

Nervous control of swallowing

A

Swallowing centre in medulla

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9
Q

Primary Peristalsis is

A

Induced by swallowing - contraction above bolus, relaxation below bolus

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10
Q

Secondary peristalsis is

A

Not induced by swallowing, stimulation of oesophageal sensory receptors wanting to get stuff out of there (can also be acid going back up)

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11
Q

Lower Oesophageal Sphinchter muscle type

A

Smooth

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12
Q

Lower oesophageal sphinchter cell type change

A

Squamous -> columnar (squamocolumnar junction)

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13
Q

GORD

A

Gastro-oesophageal reflux disease

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14
Q

Transient Relaxation of Oesophageal Sphinchter

A

Transient = not when food trying to get in

Occurs normally to let air in

Bad if happens too often as GORD from acid

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15
Q

Causes of GORD

A
  1. High acid in fundus
  2. Hiatus hernia = easy for acid to get into oesophagus
  3. Impaired oes. Peristalsis = cant clear the acid
  4. LOS not tight (from eg alcohol )
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16
Q

GORD Complications

A

Reflux Oesophagitis ->
Oesophageal stricture = fibrosis ->
Barrett’s Oesophagus ->
Cancer

17
Q

Oesophagitis causes

A

GORD
Medication
Infections eg Herpes, candidiasis

18
Q

Stricture =

A

Tightening due to fibrosis

19
Q

Barrett’s Oesophagus cell type chnage

A

Squamous -> Columnar
(Intestinal metaplasia)

20
Q

Screening tool for oesophageal cancer

A

Looking for Barrett’s Oesophagus as it is pre-cancerous for (lower) oesophageal cancer (adenocarcinoma)

21
Q

Squamous Cell Carcinoma occurs where

A

Upper Oesophagus

22
Q

Eosoniphlic Oesophagitis is

A

Asthma for the oesophagus

23
Q

Zenker’s Diverticulum

A

Pharyngeal pouch due to excessive pressure = some food can’t get to stomach = regurgitate

24
Q

Physical Patholgoies to Oesophagus Present with dysphasia mostly effecting _____

A

Solids (as blocked)

25
Q

Motility disorders effecting oesophagus present with dysphagia impacting _____

A

Both solid and liquid

26
Q

Diffuse Oesophageal Spasm

A

Non-Peristaltic = Not contracting at same time

27
Q

Achalasia

A

Degeneration of nerves in Oesophagus

28
Q

Scleroderma

A

Fibrosis of Submucosa and muscle oesophagus