Oesophageal cancer Flashcards

1
Q

Adenocarcinoma

A

Most common type in UK/USA

Lower third- near the junction

Risk factors
- GORD
- Barret’s oesophagus
- smoking
- achalasia
- obesity

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2
Q

Squamous cell cancer

A

Most common in developing world

Upper two thirds of oesophagus

Risk factors
- smoking
- alcohol
- achalasia
- Plummer Vinson syndrome
- diets rich in nitrosamines

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3
Q

Features

A

Dysphagia is most common presenting symptom

Anorexia and weight loss

Vomiting

Hoaresness, melaena, cough

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4
Q

Diagnosis

A

Upper GI endoscopy with biopsy

Endoscopic US preferred method for locoregional staging

CT CAP for initial staging

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5
Q

Treatment

A

Operable disease best managed by surgical resection (Ivor-Lewis type oesophagectomy)

Biggest surgical challenge is anastomotic leak with intrathoracic anastomosis resulting in mediastinitis

Adjuvant chemotherapy

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