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Oral Pathology > Odontogenic Tumors > Flashcards

Odontogenic Tumors Flashcards

1
Q

A benign odontogenic epithelial tumour is characterized by local invasive lesion

A

Benign Epithelial odontogenic Tumors / Ameloblastoma

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2
Q

Origin of ameloplastoma / benign epithelial odontogenic tumours

A

EO,REE ,DL,ERM and ERS

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3
Q

Types of ameloplastoma

A

Conventional or Multicystic Intraosscous Ameloblastoma

Unicystic Ameloblastoma

Peripheral Amcloblastoma

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4
Q

Age - 40-50 years / Sex-Males / Site / Mandible>Maxilla .P-M area Body .Asanding Ramus and Angle of Mandible / Sign & symptoms. Asymptomatic bony swelling is characterized by locally invasive behavior, slowly growing ,facial deformity & expansion of jaw ,which leads to Egg-Shell Cracking and pathological fracture with resorption and mobility of related teeth

A

Clinical picture of ameloplastoma

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5
Q

The lesion is characterized by ill-defined multilocular radiolucent area

Resorption of related roots

Some cases related to un- crupted tooth or teeth (Impacted third molar )

It may appcar as a unilocular radiolucent area

A

Radiological features of ameloplastoma

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6
Q

D/D of ameloplastoma

A

Odontogcnic Myxoma

Uní cystic ameloplastoma

Dentigerous cyst

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7
Q

Some cases of particular odontogenic tumour appear as soup babble appearance or honey combed appearance

A

Ameloplastoma/ benign epithelial odontogenic tumor

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8
Q

Variations of ameloplastoma in H.P. / histopathological types of ameloplastoma

A

Folicular aneloplastoma

Plexiform ameloplastoma

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9
Q

The lesion reveals proliferation odontogcnic epithelial cells in the form of ‼️ islands ‼️, which surrounded a multiple cystic spaces. These spaces are lined by peripheral single layer of tall columnar cells
( Ameloblastic-like Cells with reversed polarity ) and central loosely arranged cells ( Stellate Reticulum -
like Cells).

A

Follicular Ameloblastoma

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10
Q

Regarding the ameloplastoma ,The lesion reveals proliferation odontogcnic epithelial cells in the form of ?

A

‼️ islands ‼️

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11
Q

The lesion reveals proliferation odontogenic epithelial cells in the form of ‼️ anastomosing strands or
cords ‼️ , Each strand consists of a peripheral single layer of tall columnar cells (Ameloblast-Like Cells
with reversed polarity) and central looscly arranged cells( Stellate Reticulum -like Cells)

A fibro-vascular CT. stroma supported the lesion

A

Plexiform ameloplastoma

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12
Q

Regarding the plexiform ameloplastoma , The lesion reveals proliferation odontogenic epithelial cells in the form of ?

A

‼️ anastomosing strands or cords ‼️

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13
Q

Unicystic Ameloblastoma is ?

A

A benign odontogenic epithelial tumor

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14
Q

Origin of Unicystic Ameloblastoma ?

A

Wall of dentigerous cyst

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15
Q

Age :-in children
Site:-in maxilla at anterior area

A

Clinical features of unicystic ameloplastoma

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16
Q

A benign odontogenic eithelial tumor with locallv invasive lesion occurs intra-osseous and extra-Osseous

A

calcing tpilhelial odontogenic Turmos / Pindborg’s Tumuor

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17
Q

Origin of calcing tpilhelial odontogenic Turmos / Pindborg’s Tumuor

A

Stratum Intermedium Layer Of Enamel Organ

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18
Q

Site,-Mand >Max, P-M area / Sign & symptoms .Asymptomatic bony swelling is characterized by slowly growing .B-L cortical bones
expansions, mobility and resorption of relate teeth

A

Clinical features of calcing tpilhelial odontogenic Turmos / Pindborg’s Tumuor

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19
Q

X - ray of calcing tpilhelial odontogenic Turmos / Pindborg’s Tumour

A

X-Ray,-The lesion appears as ill-defined unilocular or multilocular radiolucent area involved and
resorped adjacent roots. Which surrounded an unerupted tooth and is localized by radiopaque rim.
‼️ A calcified masses can be seen within radiolucent area with a variable their sizes so that is called CEOT‼️

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20
Q

Regarding the Pindborg’s tumour ‼️ A calcified masses can be seen surrounded the radiolucent area with a variable their sizes so that is called CEOT‼️

A

False ‼️ A calcified masses can be seen within radiolucent area with a variable their sizes so that is called CEOT‼️

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21
Q

The lesion reveals proliferation odontogenic epithelial cells ‼️ in the form of islands or nests ‼️ These cells
are characterized by ‼️ polyhedral -shaped cells with prominent intracellular bridges between them,‼️
‼️ nucular pleomorphism in their number. size and shape ‼️
‼️ homogeneous cosinophilic amyloid-like materials ‼️ can be scen separating these cells and undergo to
the ‼️ calcification ‼️ so which is called ‼️ (Liesegang Ring Calcifications) ‼️
starch or cHlo
A Fibro-vascular ‼️ C.’T. stroma supproted the lesion‼️

A

Histopathological features of Pindborg’s tumour

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22
Q

A benign odontogenic ectomesenchymal tumour occurs intra-oral or extra-oral postions.

A

Epithelial Odontogenic Tumours With Ectomesenchymal

Ameloblastomic Fibroma

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23
Q

Origin of Epithelial Odontogenic Tumours With Ectomesenchymal

Ameloblastomic Fibroma

A

Dental papilla, dental follicle and periodental ligament.

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24
Q

Clinical Features of Epithelial Odontogenic Tumours With Ectomesenchymal

Ameloblastomic Fibroma

A

Age,-30-40 years Site;- P-M arca ,the body and ramus of the mandible …
D/D…Amcloblastoma
Sign & symptoms ,
Asymptomatic bony swelling is characterized with slowly growing, B.-L. cxpansions and associated
with a crown or a root of uncrupled tooth

25
Q

X ray of Epithelial Odontogenic Tumours With Ectomesenchymal

Ameloblastomic Fibroma

A

Well-defined unilocular or multilocular radiolucent arca is surrounded by th radiopaque
margin and associated with a crown or a root of uncrupted tooth

26
Q

Histopathological Fcatures of Epithelial Odontogenic Tumours With Ectomesenchymal

Ameloblastomic Fibroma

A

The lesion consists of a highly cellular connective tissue stroma as well as primative dental
papilla (pulp tissue of developing tooth ) ,which is mixed with proliferation odontogenic epithelial
cells in the different forms including anastomosing cords, strands , finger -like projections and
follicles as well as enamel organs .The cells of these forms resemble cells of ameloblastoma.
If the lesion contains dentine ,which is called Ameloblastic Fibro-dentinoma
But, if it contains enamel) dentin and cementum;which is called Ameloblastic Fibro-odontoma
Odontoameloblastoma; it is ameloblastoma -like structure with enamel and dentin

27
Q

A benign odontogenic epithelial and ectomesenchymal lesion .

A

Calcifying Odontogenic Cyst
A (Gorlin’s Cyst)

28
Q

Clinical Features of Calcifying Odontogenic Cyst A (Gorlin’s Cyst)

A

Age:- Below 40 years
Site :-Max. =Mand. especific at anterior maxillary canine region
If it occurs peripheral ,the anterior gingiva is a more favourable site .
Sign & symptoms :Asymptomatic bony swelling is slowly growing and causes B-L. expansions
with mobility of related teeth . in some cases, which is associated with crown of an un-erupted
tooth

29
Q

X-Ray of Calcifying Odontogenic Cyst A (Gorlin’s Cyst)

A

Well defined unilocular or multilocular radiolucet area contains a calcified masses or
radionaque masses and is surrounded
by sclerotic margin

30
Q

Histopathological Feature of Calcifying Odontogenic Cyst A (Gorlin’s Cyst)

A

The lesion is characterised by cystic spaces lined by peripheral single layer of columnar cells ( ameloplast cells with reversed polarity ) and central stellate reticulum like cells . Areas of eosinophilic structures called ghost cells which undergo to calcification as well as dentine and enamel -like structures can be seen.The
lesion is supported by a vascular fibrous C. I. stroma and in some cases, it may be associated with
Odontome

N.B.:
A sold pattern Is a more aggressive than cystic one.

31
Q

Ectomesenchymal Odontogenic Tumours

Odontogenic Fibroma

A

A benign ectomesenchymal odontogenic tumour

32
Q

Origin of A benign ectomesenchymal odontogenic tumour

A

Dental papillae ,dental follicles and pcriodontal ligaments

33
Q

Clinical Features of Ectomesenchymal Odontogenic Tumours

Odontogenic Fibroma

A

Site,- P-M areas, related to root of an unerupted tooth
/Sign & symptoms : Asymptomatie bony swelling is characterized by slowly growing and bony
expansions ,which is associated with the root of an erupted tooth or the crown of an unerupted
tooth or at place of a missing tooth

34
Q

X-rey of Ectomesenchymal Odontogenic Tumours

Odontogenic Fibroma

A

Non-specific ;well defined uni or multilocular radiolucent area contains calcified
masses and surrounded by sclerotic margin

35
Q

Histopathological Features of Ectomesenchymal Odontogenic Tumours

Odontogenic Fibroma

A

The lesion consists of a highly cellular C.T. stroma as well as primitive dental papilla (pulp tissue of
developing tooth ), which surrounds an arrested odontogenic cpithelial cells as well as enamel organs
Areas of calcification as well as dentine , cementum and enamel -like structures can be scen.

36
Q

A benign ectomesenchymal odontogenic tumour is characterized by a local invasive and a highly
recurrent lesion.

A

Odontogenic Myxoma

37
Q

Origin of odontogenic myxoma

A

Dental papillae, dental follicles and periodontal ligaments

38
Q

Clinical Features of odontogenic myxoma

A

Duration of growth; A rapidly growing lesion as a result of accumulation of myxoid ground
substances
Sign & symptoms : Asymptomatic bony swelling involved an unerupted tooth

39
Q

X-Ray of odontogenic myxoma

A

Well defined multilocular radiolucent area as well as (Soap -Bubble ) appearance).

40
Q

Histopathological Feature of odontogenic myxoma

A

The lesion is characterized by a cellular stroma with a highly concentration of myxoid ground
substances and a few stellate -like cells have a long anastomosing processes as well as fibroblast
-like cells .Areas of calcified foci may be seen within the tumor with clusters of an arrested
odontogenic epithelial cells

41
Q

Complications of Odontogenic myxoma

A

A highly recurrent rate Why???????????????
An uncapsulated Lesion
ground substance.
Its content resembles a gelatine subsfance so it is very difficult to be controlled during surgery

42
Q

A benign ectomesenchymal odontogenic tumour is characterized by related to a vital tooth

A

Benign Cementoblastoma

(True Cementoma)

43
Q

Clinical Features of Benign Cementoblastoma

(True Cementoma)

A

Age:-Below 20-30 years
Site:- premolar - molar Fandiblar area 5 Ksociated with & vital coot, pu
Sign & symptoms : Asymptomatic bony swelling is characterized by slowly growing with bony
expansions
and attached with a vital tooth

44
Q

X ray of Benign Cementoblastoma

(True Cementoma)

A

Radiopaque masses is surrounded by radiolucent margin and attached to a vital tooth

45
Q

Histopathological Frature of Benign Cementoblastoma

(True Cementoma)

A

A calcified masses or foci with a variable their sizes are characterized by prominent dark
basophilic incremental lines and cementoblast -like cells are inside lacunae as well as Cementum
-Like structures ,which is surround by extensive
sheets of uncalied matrix, I
suDported by a fibro-vascular connective tissue stroma,

46
Q

A benign odontogenic epithelial and cctomesenchymal tumor
Or a hamartomatous (malformation ) lesion rather than a ncoplastic lesion occurs in the oral cavity
and contains the calcified dental tissucs. E. D C

A

odontome
or Odontoma

47
Q

Types Of Odontomes.

A

Compound Odontome
Complex Odontomc

48
Q

Site of Compound Odontoma

A

Anterior part of maxilla

49
Q

Site of Complex Odontoma

A

Posterior area of the mandible

50
Q

Histopathological feature of compound odontome).

A

The lesion reveals a vaso-fibrous CT. stroma , which arounds and supports a galcified masses as well
as tooth -like structures (including enamel matrix .dentine and cementum

51
Q

Histopathological Feature of complex odontome.-

A

As well as the compound odontore except it contains haphazardly arranged calcified structures or
denticles (pulp tissue cementum .dentine
and enamel spaces ) and is supported by fibro-vascular
C.T, stroma.

52
Q

A benign developmental mixed Odontogenic tumour

A

The Variants Of Odontomes
Invaginated Odontome (Dens Invaginatus or Dens-in-Dens)

53
Q

Site of The Variants Of Odontomes
Invaginated Odontome (Dens Invaginatus or Dens-in-Dens)

A

Permancnt maxillary latcral incisors

54
Q

Pathogencsis.- As a result of external cvagination of a part of camel organ due to trauma or as a
result of ..genetic abnormality as where as in Mongoloid Stock….

A

Evagination Odontome; (Dens Evaginatus)

55
Q

Site of Evagination Odontome; (Dens Evaginatus)

A

occlusal surface of a permanent lower premolar

56
Q

A benign developmental odontogenic lesion is characterized by ectopic enamel formation

A

Enamcl Pearls

57
Q

Site of Enamcl Pearls

A

In bifuraction of a permanent lower molar tooth (PLMT) at amelocemental

58
Q

a malignant tumour is originated from Epithclial Tissues

A

Carcinoma

59
Q

a malignant tumour is originated from …Mesenchymal Tissus (Connective Tissues).

A

Sarcoma

Oral Pathology (6 decks)

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