Ocular Physiology 1 Lacrimal Apparatus Flashcards

1
Q

What type of gland is the lacrimal gland?

A

Tubuloacinar gland derived from surface ectoderm

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2
Q

What lines the lacirmal ducts?

A

Low columnar or cuboidal epithelium

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3
Q

What nerve innervate the lacrimal gland?

A

Postganglionic secretomotor fibres (from the pterygopalatine ganglion) hitch hike on the zygomaticotemporal and lacrimal nerves

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4
Q

Where else do lacrimal secretions come from

A

Accessory lacrimal tissue in the conjunctiva

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5
Q

What mediates reflex tearing?

A

Parasympathetic nerves that stimulate myoepithelial cells lining the lacrimal acini, causing them to contract

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6
Q

Where do the parasympathetic fibres that stimulate reflex tearing originate?

A

Superior salivatory nucleus

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7
Q

How to sympathetic nerves influence tear production?

A

Altering blood flow to the lacrimal gland

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8
Q

What are the layers fot he tear film?

A

Lipid layer
Aqueous layer
Inner hydrophilic mucin layer

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9
Q

How thick is the mucous layer of the tear film?

A

30 micrometers

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10
Q

Where are mucin secreting goblet cells concentrated?

A

Inferonasally in the conjunctiva

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11
Q

What is the stability of the tear film dependent on ?

A

Epithelial glycocalyx, antievaporative effects of the lipid layer, viscous properties of the tears imparted by the mucin layer

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12
Q

What is normal tear film break up time?

A

10-30 seconds

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13
Q

What is the maximal volume of the conjunctival sac?

A

20 microlitres

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14
Q

What is normal tear volume

A

6-7 microlitres

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15
Q

What % of an average drop of medication is retained

A

20%

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16
Q

What is a normal Schirmer’s test?

A

15-25mm of wetting over a period of 5 minutes

17
Q

How are tears biochemically formed

A

Secretion from the acinar region of the lacrimal gland is an ultrafiltrate of plasma
Later modified by ductal secretion of potassium chloride

18
Q

What is the osmolarity of the aqueous layer? pH?

A

Osmolarity is that of normal saline
pH 7.4

19
Q

Why is the glucose concentration in the aqueous layer lower than that of plasma?

A

Precorneal tear film and limbal vessels supply the corneal epithelium with glucose