OCULAR MOTOR NERVES Flashcards
III nuclear complex - where
midbrain at the level of the superior colliculus, ventral to the Sylvian aqueduct
Levator subnucleus - where and what causes lesion
unpaired caudal midline structure that innervates both levator muscles. Lesions → bilateral ptosis
Superior rectus subnuclei - what innervates and what causes lesion
are paired: each innervates the respective contralateral superior rectus. A nuclear third nerve palsy will therefore spare the ipsilateral, and affect the contralateral, superior rectus
Medial rectus, inferior rectus and inferior oblique subnuclei- what innervate and what causes lesion
are paired and innervate their corresponding ipsilateral muscles. uncommon. The most frequent causes are vascular disease, primary tumours and metastases
Involvement of the paired medial rectus subnuclei - what causes
cause a wall-eyed bilateral internuclear ophthalmoplegia (WEBINO), characterized by exotropia with defective convergence and adduction
WEBINO
Involvement of the paired medial rectus subnuclei cause a wall-eyed bilateral internuclear ophthalmoplegia (WEBINO), characterized by exotropia with defective convergence and adduction. Lesions involving the entire nucleus are often associated with involvement of the adjacent and caudal fourth nerve nucleus
Benedikt syndrome
involves the fasciculus as it passes through the red nucleus and is characterized by ipsilateral third nerve palsy and contralateral extrapyramidal signs such as hemitremor
Weber syndrome
involves the fasciculus as it passes through the cerebral peduncle and is characterized by ipsilateral third nerve palsy and a contralateral hemiparesis
Nothnagel syndrome
involves the fasciculus and the superior cerebellar peduncle and is characterized by ipsilateral third nerve palsy and cerebellar ataxia
Claude syndrome
combination of Benedikt and Nothnagel syndromes (hemitremor and cerebellar ataxia)
III - pathway
Nuclear complex, Fasciculus, Basilar, Intracavernous, Intraorbital
Superior division innervates
levator and superior rectus muscles
Inferior division innervates
the medial rectus, inferior rectus and inferior oblique muscles. The branch to the inferior oblique also contains preganglionic parasympathetic fibres from the Edinger–Westphal subnucleus, which innervate the sphincter pupillae and the ciliary muscle
Lesions of the inferior division - sings
limited adduction and depression, together with a dilated pupil
pupillary involvement as the only sign of third nerve palsy - causes
basal meningitis, uncal herniation