Ocular Anatomy (with some accidental Disease mixed in) Flashcards
What is sclerotic scatter used to look for?
Corneal edema
What is the illumination angle for sclerotic scatter?
60 degrees
What is an optic section used for?
Depth assessments - angle, corneal lesions
About how wide should an optic section be?
0.5mm
What is specular reflection used for?
Evaluate corneal endothelium and anterior/posterior lens surfaces
What is indirect illumination used to view?
Non-opaque corneal lesions
When a cobalt filter is used without fluorescein, what is highlighted, and in what color, that is commonly found in keratoconus?
Fleischer rings - corneal iron rings
Appear black
What may happen to IOP in cases of severe chemical burns?
Increase
Why are alkali burns worse than acid burns?
They raise tissue pH, breaking down fatty acids, allowing for faster penetration
Which are more common, alkali burns or acid burns?
Alkali - 2x as common
What is the most common cause of alkali burns?
Calcium hydroxide
In which type of chemical burn is limbal blanching more common?
Alkali
What are the common symptoms of a corneal abrasion?
Pain FBS Photophobia Tearing Blurred vision Mild AC reaction Miotic pupil
A corneal abrasion typically stains with fluorescein, but doesn’t have what?
SEIs
What should always be done before removing a corneal foreign body?
Check VA
What is hyphema?
Blood in the AC
What systemic diseases may cause hyphema?
Sickle-cell retinopathy
Clotting disease
(others)
What typically causes hyphema?
Trauma to the iris and/or ciliary body
What should NOT be performed on a patient with hyphema?
Gonio
Scleral depression - they can cause re-bleeds
How long after an injury that causes hyphema can gonio be performed?
About 1 month
What are some additional signs associated with hyphema?
Iris sphincter tear Iridodialysis Cataract (traumatic) Vossius ring on anterior lens capsule Commotio retinae Angle recession
Why might there be a significant IOP increase in a patient with hyphema?
Blood cells block the TM, blocking outflow
What should you ask about if a patient presents with an idiopathic hyphema?
Use of blood thinners
What tests might you order if a patient presents with idiopathic hyphema?
CBC
Prothrombin time/partial thromboplastin time
Sickle cell screen
Which ethnicities have a higher prevalence of sickle cell?
African American
Mediterranean
Which type of intraocular foreign might cause significant inflammation?
Iron
Steel
Copper
Vegetable matter
What bone breaks in an orbital blow out fracture?
Maxillary bone
A patient presents with a blow out fracture and complains of loss of sensation of the cheek. What is the probable cause?
Damage to the infraorbital nerve
What is commotio retinae of the macula termed?
Berlin’s edema
What is iridodialysis?
Disinssertion of the iris root from the ciliary body
If a patient has an iridodialysis, what should they be monitored for?
Angle recession glaucoma
What is Purtscher’s retinopathy commonly associated with?
Chest compressing trauma
What characterizes Purtscher’s retinopathy?
Diffuse retinal hemorrhages
Exudates
Cotton wool spots
Acute pancreatitis may also cause this type of retinopathy that is commonly associated with chest-compressing trauma.
What is: Purtscher’s retinopathy
What does choroidal rupture usually appear as?
Single or multiple areas of subretinal hemorrhage, usually within the temporal posterior pole, with crescent shaped tears concentric to the optic nerve head
Choroidal rupture occurs in 5-10% of what?
Blunt trauma
What is the name for the most superficial portion of the orbicularis oculi?
Muscle of Riolan
What is the function of the Muscle of Riolan?
Keeps lid margin apposed to the globe during eye movement
Do the meibomian glands arise anterior or posterior to the Muscle of Riolan (gray line)?
Posterior
Which is the thinnest of the corneal layers?
Endothelium
What are the layers of the cornea from anterior to posterior?
Epithelium Bowmans Stroma Descemet's Endothelium
Which layer of the cornea thickens with age?
Descemet’s membrane
What vascular system nourishes the lens during fetal development?
Cloquet’s canal (hyaloid vascular system)
What is a remnant of Cloquet’s canal left on the posterior lens called?
Mittendorf dot
What is a Bermeister Papilla?
Remnant of cloquet’s canal left on the optic disc
What 3 cell types are found within the foveola?
PRs (cones)
Glial cells
Muller cells
What 5 retinal layers are found within the foveola?
RPE PRs ELM ONL Henle's fiber layer ILM
What is the size of the fovea?
1.5mm or 1500 micrometers or 1 DD
What are the approximate thickness of the cornea?
Cornea - 550 microns
What is the thickness of the thinnest part of the choroid, and where is it located?
Ora serrata
.1mm
What is the thickness of the thickest part of the choroid, and where is it located?
Posterior pole
.2mm
How thick is the thickest part of the sclera, and where is it located?
1.0mm
Near the ONH
Where is the thinnest part of the sclera, and what does it measure?
Insertions of the rectus muscles
.3mm
How thick, and where is the thickest part of the retina?
Papillomacular bundle
.23mm
How thick, and where is the thinnest part of the retina?
.1mm
Foveola
What are the 2 functions of the ciliary body?
Accommodation
Aqueous humor formation
What 2 cranial nerves transmit parasympathetic innervation to ocular structures?
CN 3
CN 7
Where do the parasympathetics begin for CN 3?
Edinger Westphal Nucleus
What structures and receptors are innervated by the parasympathetics from CN 3?
Ciliary body - M2 and M3 receptors
Sphincter muscle - M3 receptors
From where does the Edinger Westphal nucleus arise?
Midbrain
Where do the parasympathetics begin for CN 7?
Lacrimal nucleus
From where does the lacrimal nucleus arise?
Pons
What structures and receptors are innervated by the parasympathetics from CN 7?
Lacrimal gland - M2, M3 receptors
What is the course of the parasympathetics that arise from CN 3?
Edinger Westphal nucleus
Ciliary ganglion
Innervates ciliary body and sphincter muscle
What is the course of the parasympathetics that arise from CN 7?
Lacrimal nucleus
Sphenopalatine ganglion
Innervates lacrimal gland
Parasympathetics to the eye innervate what 3 structures?
Lacrimal gland (CN 7) Ciliary muscle (CN 3) Sphincter muscle (CN 3)
What 3 structures make up the uvea?
Iris
Ciliary body
Choroid
What is required for the formation of a CNVM?
A break in Bruch’s membrane
What are 4 conditions that can cause a break in Bruch’s membrane?
Exudative ARMD
Lacquer cracks
Angioid streaks
Histoplasmosis
What are the 2 xanthophyll pigments found in the macula?
Lutein
Zeaxanthin
What is the relationship of lutein and zeaxanthin to ARMD risk?
The act as antioxidants, and so protect against ARMD
How many layers of ganglion cells are contained in the macula?
2 or more layers of ganglion cells
What are the 2 types of sinuses within the cranium?
Air - ex. paranasal
Blood - ex. cavernous
What would be the expected facial finding in a patient with a lesion of the superior division of CN III?
Ptosis
What condition results from a lesion at the location of the ciliary ganglion?
Adie’s tonic pupil - the ciliary ganglion carries parasympathetics from CN 3 to the ciliary body and sphincter muscle
What are the findings of Adie’s tonic pupil?
Unilateral dilated pupil
Which nervous system is affected in Adie’s tonic pupil?
Parasympathetic - sympathetic takes over and dilates the pupil
What drug is used for diagnosis of Adie’s tonic pupil?
Pilocarpine 0.125%
Patient’s with Adie’s tonic pupil will have a delayed what?
Light response
Near response
Why do patient’s with Adie’s tonic pupil have a delayed light and near response?
There is a lesion of the ciliary ganglion, which is responsible for both the light and near response
Which cranial nerve is used for shoulder shrugging/head turning?
XI - accessory
The optic nerve gives off fibers to what 3 structures?
LGN
Pretectal nucleus
Superior colliculus
Where do preganglionic parasympathetic fibers that course to the pupil originate?
Edinger Westphal nucleus
Where do postganglionic parasympathetic fibers that course to the pupil originate?
Ciliary ganglion
What bones make up the medial wall of the orbit?
Sphenoid (body)
Maxilla
Ethmoid
Lacrimal
What bone makes up the majority of the floor of the orbit?
Maxillary bone
What degree of abduction makes the inferior rectus the primary depressor?
23 degrees
Which muscle cause intorsion, abduction, and depression?
Superior oblique
When are the oblique muscles responsible for elevation and depression?
When the eye is adducted 51-55 degrees
If a patient is instructed to look straight up, which muscles are performing this action?
Superior rectus
Inferior oblique
Where does the inferior oblique muscle start its course?
Maxillary bone
Which 2 bones make up the lateral wall of the orbit?
Zygomatic bone
Greater wing of sphenoid
(Lateral wall = Great-Z)
The bulbar conj and ciliary body both receive part of their blood supply from which vessels?
Anterior ciliary artery
What comprises the major arterial circle of the iris?
Long posterior ciliary arteries
Anterior ciliary arteries
Where is the major arterial circle of the iris located?
In the ciliary body
Why does a uveitis patient have inflammation of the ciliary body and circumlimbal injection?
Because they are both supplied by the anterior ciliary arteries
Lateral conj lymphatics drain into what?
Preauricular lymph nodes
Medial lymphatics drain into what?
Submandibular lymph nodes
Which glands lubricate the eyelashes?
Glands of Zeis
What is a second major function of the glands of Zeis?
Assist the glands of Moll and meibomian glands to produce the lipid layer of the tear film
Which layer of the tear film is secreted by blinking?
Lipid layer
What produces the lipid layer of the tear film?
Goblet cells
A deficiency in what will cause decreased production from goblet cells, causing evaporative dry eye?
Vitamin A
Which layer of the eyelid contains goblet cells?
Palpebral conjunctiva
What pupil abnormality would be most prevalent in the light?
Adie’s tonic pupil - (acute, dilated pupil)
Which pupil abnormality is most prevalent in the dark?
Horner’s