Oct15 A1,2-Mood Disorders Introduction Flashcards

1
Q

nuance to know in mood disorders

A
  • episodes and disorders are diff things described
  • criteria help dx an episode
  • then dx a disorder in a certain way
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2
Q

3 groups of symptoms for depression episode dx and done how

A
  • feeling (2)
  • physical (4)
  • thinking (3)
  • must have 5 of 9 for 2 weeks* AND see significant clinical distress or impairment (occupational, social, other) AND exclude substances (drugs and meds) or medical causes
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3
Q

2 ‘‘feeling’’ sx of depression

A
  • depressed mood (sadness or numbness)

- loss of interest (anhedonia)

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4
Q

4 ‘‘physical’’ sx of depression

A

-sleep changes (insomnia. specifically initial insomnia most frequently and sometimes early awakening insomnia) (rarely, atypical = sleep too much)
-decrease in apetite
(bc of anhedonia) + weight changes (rarely, atypical = eat too much and gain weight)
-loss of energy and fatigue
-motor slowing (possibly with pain), agitation

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5
Q

3 ‘‘thinking’’ sx of depression

A
  • poor concentration, indecisiveness, mental slowing
  • worthlessness and guilt (for things done before, which is normal, or things it’s abnormal to be worried about)
  • suicidal ideation
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6
Q

types of insomnia

A
  • initial insomnia = beginning of the night (can’t fall asleep) = most common in depression. also bc of stress in life
  • middle insomnia (interruptions in the night)
  • terminal insomnia (early morning awakening) (also possible in major depression but is more serious)
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7
Q

continuum of suicidal thoughts

A
  1. I wish I wasn’t around, I wasn’t born, I didn’t wake up
  2. It wouldn’t matter if I fell, if I got hit by a car
  3. plan suicide
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8
Q

concept about depression tx

A

each category of symptoms (feeling, physical, thinking)

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9
Q

antidepressants in depression

A
  • increase mood and sense of well being

- helps for the physical sx

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10
Q

social support in depression

A

helps being in new environment being isolated is a risk factor for depression

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11
Q

structured physical activity in depression

A

for mild to moderate depression

  • helpful for tx
  • getting things done, going out the house regularly, etc.
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12
Q

sleep hygiene in depression

A
  • sleep 7 to 9 hours in one period over 24 hours
  • usually between 11 pm and 7 am
  • 5 hours of continuous sleep helps you get 80% of sleep debt so is very important (so pt woke up at 4 or 5 am = less worried than if wake up at midnight)
  • no naps
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13
Q

light therapy in depression

A

light therapy lamps to use if people have seasonal frequency to their illness

  • schedule thing
  • wake up early to expose themselves to light
  • start to use usually in November
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14
Q

cognitive behavioral therapy and interpersonal therapy (IPT) in depression

A

helpful, especially for the thinking sx (poor conc, mental slowing, indecisiveness , worthlessness and guilt + suicidal ideation)

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15
Q

mania episode groups of sx + dx done how

A
  • feeling (1)
  • physical (3)
  • thinking (4)
  • need 4 out of 8 sx for 1 week* AND see significant clinical distress or impairment (occupational, social, other) AND exclude substances (drugs and meds) or medical causes
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16
Q

feeling sx in mania (1)

A

elevated euphoric mood + sometimes irritable (when know they’re annoying for others after many episodes)

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17
Q

physical sx in mania (3)

A
  • decreased need for sleep (really energized, do same nbr of activies as usually but in 2-3 hours)
  • talkative and pressure speech (faster speech rate)
  • psychomotor agitation
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18
Q

thinking sx in mania (4)

A
-increased goal-directed activity
(busy and organized schedule, move a lot, understand others well, very focused, feel like given a mission, do mass communication, very distractible)
-flight of ideas, racing thought
-distractibility
-pleasurable risky behavior
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19
Q

hypomania episode criteria and dx done how

A
  • feeling (1)
  • physical (3)
  • cognitive and thinking (4)
  • need 3 (if expansive elevated mood) or 4 (if irritable mood) out of 8 sx for 4 week* AND change in functioning WITHOUT impairment AND exclude substances (drugs and meds) or medical causes
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20
Q

feeling sx (1) in hypomania episode

A

elevated, expansive or irritable mood

21
Q

physical sx (3) in hypomania episode

A

-decreased need for sleep
-talkative pressured speech
-psychomotor agitation
(same physical sx as mania episode)
enjoy it bc can get a lot done

22
Q

cognitive, thinking sx (4) in hypomania episode

A

-increased goal-directed activity
-flight of ideas, racing thoughts
-distractibility
-pleasurable, risky behaviour
(same as thinking sx of mania episode)

23
Q

problem of misdiagnosing bipolar type 2 (depression + hypomania) patients by saying they have depression

A

we then give them an antidepressant and they go into full mania (meaning we switched them into bipolar type 1)

  • have to remove antidepressant
  • keep them on usual med (mood stabilizer) for bipolar disorder
  • importance of hx and asking about sx after start the meds*
24
Q

tx principle in manic and hypomanic episodes

A

specific tx approaches for each sx group

25
Q

tx in mania

A
  • mood stabilizer (NO antidepressant) = helps feeling sx
  • sedative, quiet physical location and less or no socializing help for physical sx (last one for reputation)
  • brief focused interactions, tell them the painful consequences, decrease environment stim, temporarily restrict access to risky activities, promote relaxation = helps for thinking sx
26
Q

2 categories of mood disorders in the DSM-V

A
  • bipolar and related disorders

- depressive disorders

27
Q

3 types of bipolar and related disorders

A
  • bipolar 1
  • bipolar 2
  • cyclothymia
28
Q

how to dx bipolar type 1

A

one manic episode + one major depressive episode

  • possible to dx it with a single manic episode (but 90% also have a major depressive episode hx, usually burnout after the manic episode, 3 months after being ‘‘high’’)
  • be careful in psychotic pts bc dangerous situations, do good hx to check if was caused by mania
  • mania + psychosis = diff tx than psychosis alone
29
Q

burnout after mania vs depression after mania

A

ask patient what they would do if had more energy

  • the manic pt tells you what they would do
  • the depressive pt can’t answer
30
Q

bipolar type 2 dx done how

A

same thing as bipolar type 1 but is one hypomanic episode + one major depressive episode
-always check if depressive pts have had a hypomania episode bc if give antidepressant to a bipolar type 2 pt, will switch into full mania (bipolar type 1)

31
Q

dopamine and NE tx vs serotonin tx

A
  • dopamine and NE for energy

- serotonin for well being

32
Q

cyclothymia dx done how

A
  • minimum of 2 years
  • hypomanic sx and depressive sx
  • sx present most of the time
  • no period of 2 months where symptom free
  • no full episodes
  • not common. usually women who have fluctuations with mood with menstrual cycle*
33
Q

types of depressive disorders (depressive disorders = 2nd thing in the mood disorder classif of DSM)

A
  1. major depression
  2. dysthymia (persistent depressive disorder, PDD)
  3. premenstrual dysphoric disorder (PMDD)
34
Q

major depression dx + tx

A
  • one major depressive episode
  • you give an antidepressant
  • meds or not, you won’t have another episode before a year just bc of the natural hx of depression so help pt in the meantime
35
Q

dysthymia (persistent depressive disorder) dx (basically depression sx most days)

A
  • minimum 2 years
  • depressed most days
  • 2+ sx present most of the time (poor appetite or overeating, insomnia or hypersomnia, low energy or fatigue, low self-esteem, poor conc or difficulty making decisions, feeling of hopelessness)
  • no period of 2 months sx free
  • no full episodes
  • possible to have both a major depressive episode and dysthymia*
36
Q

what are secondary mood disorders

A

caused by substances or meds or medical disorder

  • anything that promotes dopamine (cocaine, levodopa)
  • hypoT mimics depression. hyperT mimics mania
  • MS looks like mania in beginning and get depressed overtime
37
Q

parts of clinical assessment in psychiatry

A
  1. ID
  2. chief complaint
  3. pmhx
  4. meds
  5. psych hx
  6. fhx
  7. habits
  8. hpi
  9. personal and social hx
38
Q

how ID helps for mood disorders

A
  • age: depression risk decreses with age
  • sex: depression and bipolar II 2x more common in F. no diff M vs F for bipolar I (like schizophrenia)
  • marital status: divorced or separated = increased risk of depression
  • multiple divorcers = increased risk of bipolar
  • employment and productivity are protective
  • high income is protective
39
Q

how chief complaint helps for dx of mood disorder

A

check the feeling, physical and thinking sx

40
Q

how psych hx helps for dx of mood disorder

A
  • anxiety disorders (common). (not full blown disorder but episodes or generalized anxiety)
  • substance misuse and disorders (bipolar pts enjoy cocaine and things that mimic hypomanic or manic state. alcohol can make pt depressed later)
  • suicide attemps
41
Q

how FHx helps for dx of mood disorder

A
  • genetic predisposition to depression increases risk by 2-4x
  • familial non genetic risk (exposure to depressed parent, compromised parenting, neglect)
  • bipolar fhx increases risk of 10x (same as schizophrenia which has 1-10% baseline risk)
  • fhx of suicide attemps or completed increases risk for pt
42
Q

how pmhx helps for dx of mood disorder

A
other illnesses assoc with depression
neuro:
-PD
-epilepsy
-diabetes
-migraine
-stroke
cardiovascular:
-metabolic syndrome
-MI
other:
-lupus
-cancers
-Crohn's
-chronic illnesses (pain, IBS, fibromyalgia)
43
Q

how meds in clinical assessment in psychiatry can help for dx of mood disorders

A
  • dopamine (levodopa) assoc with mania
  • topiramate, reserpine, amiodarone (via thyroid), digoxin, phenobarbital and maybe interferon + CCB for BP are all assoc with depression
44
Q

how HPI helps for dx of mood disorders

A
  • stressful life events
  • lack of social support
  • emotional coping (is one of the 3 types of coping. is assoc with depression) = obsession over a negative event going on now or in the past. distraction, avoidance and sleep is another type of coping. problem solving and brainstorming is the best type of coping
  • negative cognitive style (make a negative evet your fault)
  • sleep-wake cycle disturbances (assoc with bipolar). travel across time zones = RF to switch from euthymia to hypomania or mania)
45
Q

how personal hx helps for dx of mood disorders

A
  • childhood SES (parental occup and educ, deprivation, poverty, safety)
  • childhood adversity (early trauma) (parental loss, physical abuse, neglect, harsh parenting, psychological. these can be caused by the parent having depression. increase risk of depression and bipolar)
  • level of education (higher is protective)
  • neuroticism (overthinking) = RF for depression, bipolar and psychosis
  • greater problems adapting life difficulties, transitions
  • high interpersonal dependence
46
Q

2 major categories of mood disorders

A
  • depressive

- bipolar (types 1 and 2)

47
Q

most common mood disorder

A

depression

48
Q

imp thing to get correct dx in mood disorders

A

search for hypomanic and manic episodes

  • inappropriate tx of bipolr I or II with antidepressant can worsen the prognosis of the mood disorder
  • can use mood disorder questionnaires to help (for lifetime sx of mania)
49
Q

conceptual model of mood disorders

A
  • non-modifiable risks (age, sex, shared genes, contact with sick relatives, bereavement, childhood adversity) and modifiable risks (acute events, chronic stressors, support, coping, medical illness, meds, anxiety disorders) define vulnerability
  • they lead to the mood sx (changes in sadness and euphoria, pleasure and interest, energy, activity, sleep, appetite and weight, psychomotor, concentration, attention, grandiose ideas, suicidal ideas)