OCD

Question 1

Broocks et al. 1998

Answer 1

Basal ganglia lesions vs. Hemifacial spasm - OCD scores higher in basal ganglia

Question 2

Nuttin et al. 2003

Answer 2

Electrical stimulation of internal capsule improves symptoms (french fries)

Question 3

Casale et al. 2011

Answer 3

Functional imaging -> inefficient thalamic gating -> hyperactivity in orbitofrontal cortex, causing intrusive thoughts (lack of evidence?) Compulsions recruit the inactive striatum to neutralise thoughts

Question 4

Basal ganglia lesions vs. Hemifacial spasm - OCD scores higher in basal ganglia

Answer 4

Broocks et al. 1998

Question 5

Electrical stimulation of internal capsule improves symptoms (french fries)

Answer 5

Nuttin et al. 2003

Question 6

Functional imaging -> inefficient thalamic gating -> hyperactivity in orbitofrontal cortex, causing intrusive thoughts (lack of evidence?) Compulsions recruit the inactive striatum to neutralise thoughts

Answer 6

Casale et al. 2011