Delusions

Question 1

Chen et al. 2004

Answer 1

PD patient with DBS - stimulation of left electrode caused jealousy. Misplaced in subthalamic nucleus. Interruption of neural circuits connecting basal ganglia?

Question 2

Blanke et al.

Answer 2

OBE -> temporoparietal junction localised from epilepsy surgery. Review of 36 patients confirms

Question 3

Klein + Hirachan 2014

Answer 3

Review- familiarity is lost because connection between self and emotion broken. More generally disconnection between frontal (emotion) and TPJ regions (self)

Question 4

Devinsky 2009

Answer 4

Right frontal lobe impaired (self-monitoring), left hemisphere exerts positive effect, provides narrator of self + false explanations

Question 5

Horikawa et al. 2006

Answer 5

Capgras - SPECT worsening of hypoperfusion in RH

Question 6

Fregoli syndrome

Answer 6

Spiked EEG activity in left temporal lobe -> RH Capgras, LH Fregoli

Question 7

PD patient with DBS - stimulation of left electrode caused jealousy. Misplaced in subthalamic nucleus. Interruption of neural circuits connecting basal ganglia?

Answer 7

Chen et al. 2004

Question 8

OBE -> temporoparietal junction localised from epilepsy surgery. Review of 36 patients confirms

Answer 8

Blanke et al.

Question 9

Review- familiarity is lost because connection between vision and emotion broken. More generally disconnection between frontal (emotion) and TPJ regions (self)

Answer 9

Klein + Hirachan 2014

Question 10

Right frontal lobe impaired (self-monitoring), left hemisphere exerts positive effect, provides narrator of self + false explanations

Answer 10

Devinsky 2009

Question 11

Capgras - SPECT worsening of hypoperfusion in RH

Answer 11

Horikawa et al. 2006

Question 12

Spiked EEG activity in left temporal lobe -> RH Capgras, LH Fregoli

Answer 12

Fregoli Syndrome