OCD Flashcards
OCD diagnostic criteria
Presence of persistent obsessions and compulsions
Rapoports case study
Charles
14 yr boy obsessed with showering washing hands
Dropped out of school in n out of hospitals
Underwent drug trial fro clomipramine but developed tolerance
MEASURES Of OCD
Maudsley Obsessive-compulsive inventory
YBOCS
MOCI
30-items
True or false
Related to checking washing slowness
0-30 score range
E.g; I frequently have to check things true or false
Y-BOCS
- Semi-structured interview
- Checklist
- ten item severity scale
0-40
16 above = ocd
Szechtman et al
When dopamine is increased in rats they tend to show repetitive behaviour
Leckman et al
Found that some forms of ocd were related to oxytocin dysfunction
Westenberg et al
Oppose leckman
Double -blind placebo study
12 patients with ocd
Half were given oxy half were placebo
No difference
Monzani et al
Large scale twin study
Found 52% concordance for MZ vs 21%
EST heritability= 48%
Ozaki et al
Found a mutation of SERT a gene responsible for low levels of serotonin in 6 members of two unrelated families with ocd
Matthiessen et al
1406 ocd patients+ other member of GP
Tried to identify genes that may be linked to ocd
PTPRD and SLITRK3 were implicated
Psychological explanation
Look book
Biological explanation
Look book
Rachman (cognitive)
Obsessive thinking is based on faulty reasoning
Behavioral explanation
Operant conditioning
Positive and negative