Impulsive Disorders Flashcards
Aim of Grant et Al
To identify clinical variables associated with treatment outcome in pg subjects receiving opiate antagonists
Hypothesis of Grant
A family history of alcoholism and stronger urges to gamble would be associated with positive outcomes for those treated with opiate antagonists.
Four conditions of grant
1st trial: placebo or nalmefene
2nd trial: placebo or naltrexone
Grant sample
284 patients
Had gambled in the last two weeks
Approx equal no. of men and women
From USA
Grant experiment design
Independent group design
1st trial doses (Grant)
25/50/100 mg per day
2nd trial doses (Grant)
50/100/150 mg per day
Measures used in Grant
Clinician-administered scales (PG-YBOCS)
Semi-structured interviews