Impulsive Disorders Flashcards

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1
Q

Aim of Grant et Al

A

To identify clinical variables associated with treatment outcome in pg subjects receiving opiate antagonists

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2
Q

Hypothesis of Grant

A

A family history of alcoholism and stronger urges to gamble would be associated with positive outcomes for those treated with opiate antagonists.

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3
Q

Four conditions of grant

A

1st trial: placebo or nalmefene
2nd trial: placebo or naltrexone

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4
Q

Grant sample

A

284 patients
Had gambled in the last two weeks
Approx equal no. of men and women
From USA

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5
Q

Grant experiment design

A

Independent group design

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6
Q

1st trial doses (Grant)

A

25/50/100 mg per day

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7
Q

2nd trial doses (Grant)

A

50/100/150 mg per day

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8
Q

Measures used in Grant

A

Clinician-administered scales (PG-YBOCS)
Semi-structured interviews

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