OC3 - activation by proteolysis

Question 1

proteolytic activation

Answer 1

not all proteins are produced in their active form, several are synthesised as larger, inactive precursor forms known as proproteins or zymogens
the inactive precursors are activated by cleavage of one or a few specific peptide bonds
an irreversible process.

Question 2

pepsinogen

Answer 2

a zymogen
produced in the stomach and cleaved in the stomach to become the active enzyme pepsin.