Obstructive Jaundice

Question 1

What enzyme conjugates bilirubin?

Answer 1

gluconuryl transferase

Question 2

How will urine and faeces be different in obstructive jaundice\?

Answer 2

pale stool and dark urine. Due to stercobilin in poo and urobilogen in pee

Question 3

What are the causes of obstructive jaundice? (7)

Answer 3

gallstones, head of pancreas tumour, cholangiocarcinoma, liver flukes, portahepatis lymphadenopathy, chronic pancreatitis and Mirrizi’s

Question 4

What is mirrizi’s syndrome?

Answer 4

Mirizzi’s syndrome is a rare complication in which a gallstone becomes impacted in the cystic duct or neck of the gallbladder causing compression of the common bile duct (CBD) or common hepatic duct, resulting in obstruction and jaundice.

Question 5

What are liver flukes?

Answer 5

parasites in the liver or bile ducts

Question 6

What are the complications of obstructive jaundice?

Answer 6

hepatorenal syndrome, portal hypertension