Obstrectical Complications Flashcards
1
Q
Preterm Labor
A
- b/w 20 and 37 wks
- uterine contractions with cervical change or dilation of 2 cm and/or 80% effaced
2
Q
PTL- etiology
A
- spontaneous
- mult gestations
- PPROM
- HTN
- cervical incompetence or uterine anomalies
- antepartum hemorrhage
- IUGR (intrauterine growth restriction)
3
Q
PTL- risk factors
A
- prev hx of PTL
- hx of second trimester abortion
- spontaneous 1st trimester abortions
- bleeding in 1st trimester
- UTI
- mult gestation
- uterine anomalies
- polyhydramnios
- incompetent cervix
4
Q
prevention of PTL
A
- infection (Cervical)
- placental-vascular
- psychosocial stress and work strain
- uterine stretch
5
Q
Infection pathway
A
- bacterial vaginosis- tx of women in preterm labor with abx
- tx cervical infections
6
Q
Cervix and PTL
A
- risk of PTL inc as cervical length dec!!! (RR 6.2 for 2.5 cm)
- US- to screen- check cervical length
- fetal fibronectin (FFN)- released in response to disruption of membranes (uterine activity, cervical shortening, infection)
7
Q
Placental-vascular pathway
A
-immunologic, vascular components, low resistance connection of spiral a’s
8
Q
Stress-Strain pathway
A
- inc release of cortisol and catecholamines
- cortisol- inc CRH- assist in labor
- catecholamines- affect blood flow and can cause uterine contractions
9
Q
Uterine Stretch Pathway
A
- uterine stretch as a result of inc volume
- risk factor in- polyhydramnios, mult gestations-
10
Q
dx of PTL
A
- 20-37 wks
- must have:
- uterine contractions
- cervical change: cervical dilation of 2 cm and/or 80% effacement
11
Q
PTL- management
A
- cervical exam- assess dilation, effacement
- evaluate for underlying correctable problems (infection)
- monitor uterine activity and fetal HR
- oral or IV hydrate
12
Q
PTL- management- 2
A
- hydration and bed rest- resolve contractions in 20%
- cultures for Group B Strep
- abx given empirically
13
Q
if no response to IV hydration and rest or dx 2 cm and/or 80% effaced- then begin?
A
tocolysis!!!
- Magnesium Sulfate
- Nifedipine
- Indomethacin (prostaglandin syn inhibitor)
14
Q
Magnesium Sulfate
A
- competes with calcium
- continue tx until received both doses of steroids
- role in neuroprotection- prevent against cerebral palsy
15
Q
Magnesium Sulfate- SE’s
A
- maternal- warmth, flushing, N/V, resp depression, cardiac conduction defects
- neonate- loss of m tone, drowsiness, lower Apgar scores
16
Q
Nifedipine
A
- oral!
- minimal maternal and fetal SE’s
17
Q
Prostaglandin Synthetase Inhibitors
A
- inhibits prostaglandin prod (induce myometrial contractions)
- used for extreme prematurity
- Indomethacin- can result in oligohydramnios, premature closure of fetal ductus arteriosis