Multifetal gestation and malpresentation Flashcards
Monozygotic twins- placenttion
depends on time of cleavage
- Dichorionic, diamniotic- 0-3 days
- Monochorionic, diamniotic- 4-8 days
- Monochorionic, monoamniotic- 9-12 days
- conjoined twins- > 13 days
Dichorionic diamniotic
- 0-3 days cleavage
- 2 chorions, 2 anions
- 30% of monozygotic twins
Monochorionic diamniotic
- 4-8 days cleavage
- 1 chorion, 2 amnions
- 69% of monozygotic twins
Monochorionic monoamniotic
- 9-12 days of cleavage
- 1% of monozygotic twins
- most dangerous- cord entanglement
- net mortality 50-80%
Monochorionic monoamniotic- conjoined twins
- 13-15 days of cleavage
- craniopagus- joined at cranium
- thoracopagus- joined at chest wall
- ischopagus- joined by coccyx and sacrum
confirmation of multiples by?
US
most important step after dxing twins
- determination of zygosity
- monozygotic
- dizygotic
US to determine zygosity
- dizygotic- diff fetal gender, thick amnion-chorion septum, peak or inverted V sign at base of septum
- monozygotic- dividing membrane is thin
- if US is not definitive- inspect placenta after delivery, DNA analysis
abnormalities in monozygotic twins- Interplacental vascular anastomoses
- 90% occur in monochorionic twins
- abortion, polyhydramnios, TTTS, fetal malformations
abnormalities in monozygotic twins- TTTS (twin twin transfusion syndrome)
- anastomses in monochorionic placenta- blood flow from 1 twin to the other
- donor twin- hypovolemia, hypotension, anemia, oligohydramnios, growth restriction
- recipient twin- hypervolemia, polyhydramnios, thrombosis, HTN, polycythemia, edema, CHF
- both at risk for HF
TTTS- dx
US
- donor twin- smaller, “stuck”, oligohydramnios
- recipient twin- larger, polydyramnios, ascites
TTTS- tx
- amniocentesis with amniotic fluid reduction
- laser photocoagulation of anastomosis vessels on placenta
abnormalities in monozygotic twins- Arterial to Arterial anastomoses
- can cause thrombosis
- recipient twin (perfused with poorly deoxygenated blood) fails to develop normally- ACARDIAC twin- no anatomic structures cephalad of abdomen
abnormalities in monozygotic twins- Umbilical cord abnormalities
- absence of umbilical a
- velamentous umbilical cord insertions occur more freq- may cause growth abnormalities
abnormalities in monozygotic twins- retained dead fetus syndrome
- if gestation is > 20 wks
- DIC in mother
- check plts and fibrinogen levels weekly
- if gestation is < 12 wks- dead fetus is reabsorbed- vanishing twin syndrome
- if > 12 wks- fetus shrinks, dehydrates- fetus papyraceus