Obstetrics Flashcards
Preeclampsia risk factors (6)
Hydatidiform mole, multiple gestational, obesity, polyhydramnios, diabetes, primigravidas
Define mild preeclampsia
Systolic > 140, diastolic > 90, proteinuria >2 gm/day, edema
What vasopressor should be used with mag toxicity and why?
Ephedrine, magnesium antagonizes the effects of alpha agonists
What happens to cardiac output at term, during labor, and immediately after delivery?
40% increase at term, 45% during labor, 60-80% increase following delivery
How much does plasma volume increase? Red cell volume?
40% plasma, 20% red cell volume
During pregnancy, what H&H signifies true anemia?
</= 33/11
What 3 changes happen to the GI system during pregnancy?
Acidity and gastric volume increase, gastric motility decrease (2/2 progesterone), GE sphincter tone decreases
When does aortocaval compression occur?
20 weeks
What happens in supine position after 20 weeks and why?
Aortocaval compression 2/2 a 50% increase in femoral venous pressure that causes a 10-15% decrease in SV and CO
During pregnancy, when is the H&H lowest and why?
30-34 weeks 2/2 plateau in volume expansion
What changes happen to RBF, GFR, and BUN/Cr? When?
They increase by 50% leading to a decrease in BUN and creatinine; 16 weeks
What happens to total protein and albumin/globulin ratio during pregnancy and its importance
Decreased; lower albumin may result in higher free blood levels of substances
Why happens to pseudocholinesterase levels during pregnancy? Does this affect your anesthetic?
Decreased, response to moderate doses of succinylcholine is not prolonged
What happens to SV, HR, and SVR during pregnancy?
SV increases by 25%, HR increases less, SVR decreases by 20%
What CNS changes occur during pregnancy?
40% decrease in MAC, 30-50% decrease in local requirements
What 3 changes occur to the airway during pregnancy?
Capillary swelling leads to mucosal enlargement, tissues become more friable, breast enlargement can cause head positioning difficulty
What happens to minute ventilation during pregnancy and why?
Increases by 50%; progesterone increased tidal volume with little change in RR
What acid/base changes occur during pregnancy?
PaCO2 is ~32 but pH is unchanged because of compensatory metabolic acidosis (HCO3 25 –> 21)
How does inhalational induction change during pregnancy and why?
Increased ratio of minute ventilation to FRC causes rapid induction and emergence
What happens to FRC during pregnancy?
Decreases 20% due to decrease in residual volume; closing capacity exceeds FRC in ~50% of supine women late in pregnancy
What happens to vital capacity during pregnancy?
Unchanged as inspiratory capacity increases and expiratory reserve volume decreases
What happens to PaO2 during pregnancy?
Increases by 10
What happens to airway resistance during pregnancy?
Decreases 2/2 progesterone
What happens to tidal volume during pregnancy?
Increase by 45%
What happens to oxygen consumption and CO2 production during pregnancy?
Consumption increase 30-40%, CO2 production increase 30-40%
What coagulation factors increase during pregnancy?
Factors I (fibrinogen), II, VII, VIII, IX, X
What is the range for leukocytosis after 12 weeks?
10500-16000
Which coagulation factors decrease during pregnancy?
Factors XI, XIII
What is the non-pregnant UBF?
50-200 ml/min
What is pregnant UBF?
10% of CO, 600-700 ml/min
How much must UBF decrease to see fetal distress?
50%
Name drugs that do not cross the placenta (5)
heparin, insulin, glycopyrrolate, non-depolarizing relaxants, succinylcholine
What is the 1st stage of labor?
start of contractions to complete cervical dilation
What nerves are involved in 1st stage of labor and what do they innervate?
T10-L1 visceral pain of contractions and cervical dilation –> uterus, cervix, upper vagina