objective 3: finding alternatives Flashcards
what is the first step in the sequence algorithm adapted from haywood?
check the formulation of the ingredient list for problematic excipients
what is the second step in the sequence algorithm adapted from haywood?
check resources for known/reported issues
what is the third step in the sequence algorithm adapted from haywood?
consider a therapeutically equivalent drug product
what are 5 excipients have reported drug interactions?
- ethanol
- cremophor
- aspartame
- propylene glycol
- polysorbate
what excipient, when administered orally, can potentially cause results in GI symptoms indicative of a sensitivity?
lactose
what 2 colorants may have a cross sensitivity with patients who have an aspirin intolerance?
- FD&C #6
- FD&C #5
what are 2 sensitivities that can manifest if given sodium metabisulfite topically?
- dermatological
- respiratory symptoms
by what name describes the three symptoms caused by an aspirin allergy?
aspirin triad (samters triad)