ObGyn2 Flashcards
Salpingitis isthmic nodosa (definition)
-Tubal diverticuli: tubal epithelium penetrates into muscularis or even serosa
Chromotubation (definition)
- Dye injected into uterus via transcervical catheter
- Tubal patency assessed via laparoscopy/laparotomy
Test used to assess tubal factor infertility
HSG: hysterosalpingogram
Risk factors for tubal infertility (x3)
- PID
- Previous pelvic or tubal surgery
- Peritoneal factors
If first step in tubal infertility assessment is abnl, it should be confirmed with:
Laparoscopy
Proximal vs. distal vs. combined tubal obstruction (tx)
- Proximal: tubocornual anastomosis
- Distal: fimbrioplasty
- Both: IVF
Tubal surgery increases the risk of:
Ectopic pregnancy
Which is more common, distal or proximal tubal disease?
-Distal, in U.S. (easier to treat surgically)
Amenorrhea (definition)
Lack of menses for 6mo
Sheehan’s syndrome vs. Asherman’s syndrome
- Secondary amenorrhea in both
- Lack of anterior pituitary function in Sheehan’s (prolactin [breast feeding], TSH [hypothyroidism], gonadotropins [amenorrhea])
First step in amenorrhea
Pregnancy test
Sheehan’s syndrome (tx)
Hormone replacement: thyroxine, cortisol, mineralocorticoid, and estrogen/progestin
5 hallmarks of PCOS
- Hirsutism
- Obesity
- Excess estrogen
- Anovulation
- Glucose intolerance/insulin resistance
Hypothyroidism to galactorrhea link
Hypothyroidism -> high TRH -> high PRL -> galactorrhea (+irregular menses d/t loss of GnRH pulsatility)
Galactorrhea (ddx x5)
- Pregnancy
- Pituitary adenoma
- Hypothyroidism
- Breast stimulation
- Chest wall trauma
Most sensitive test for pituitary adenomas/microadenomas
MRI
Primary hypothyroidism (tx)
Thyroxine
Indicated therapy for symptomatic microadenoma during pregnancy
Bromocriptine
Five causes of infertility
1) Ovulatory
2) Uterine
3) Tubal
4) Male factor
5) Peritoneal factor (endometriosis)
3D’s of endometriosis
(Though not necessary)
dysmenorrhea, dyspareunia, dyschezia
Infertility (definition)
Failure to get pregnant after 1yr of unprotected intercourse (10-15% NL)
Fecundability (definition)
Probability of pregnancy within one menstrual cycle (20-25% NL)
Assessing ovulatory factor in infertility (tests)
- BBT
- Serum progesterone
- Serum LH
Assessing uterine factor in infertility (test)
HSG, followed by hysteroscopy
Assessing tubal factor in infertility (tests)
HSG, followed by laparoscopy (gold standard)
Assessing male factor in infertility (tests)
- Volume (NL: at least 2ml)
- Concentration (NL: at least 20million/ml)
- Motility (NL: 50%)
- Morphology (NL: 30% nl)
Assessing peritoneal factor in infertility (test)
Laparoscopy
Expected temperature change in biphasic BBT chart
Increase of 0.5* C
Septic abortion (definition)
Any type of abortion associated with uterine infection
Septic abortion (mgmt)
1) Maintain/monitor BP, oxygenation, UOP
2) Broad spec ABXs (w/ anaerobic coverage)
3) Uterine curettage
Mechanism behind septic abortions
Ascending infections (polymicrobial)
Positive pregnancy, no IUP visualized and/or no chorionic villi on curettage (dx)
Ectopic pregnancy
Relative contraindications for methotrexate use (x2)
- Ectopic pregnancy >4 cm
- Presence of fetal cardiac activity
Threshold HCG level (level @ which pregnancy should be seen on US)
1500 mIU/ml