Obesity - Week 3 Flashcards
How many people in world are obese?
2.1 billion
How many obesity deaths?
300k/yr in us
What is the cost of obesity?
147 millin
Who has the highest rates of obesity?
non hispanic blacks
Who has the lowest rates of obesity?
non-hispanic asain
How much does obesity increase risk of death from all causes?
50-100%
How much can obesity decrease life span?
2-13 yrs
What shape confers the highest risk?
apple shape
What does adipose tissue secrete?
inflammatory mediators IL TNF resistin adiponectin leptin "adipocytokines"
What is apple shape?
android
What is pear shape?
gynoid
What waist hip ratio give greatest risk?
> .85 women, >.9 men
What specific group has the highest rate of being overwt or obese?
AA women
What are medications associated with obesity?
atherosclerosis DM type II osteoarthritis gout obstructive sleep apnea POS incontinence cancer depression
How does atherosclerosis relate to obesity?
low fruit and veggies
red meat raises risk
What does higher fiber diet =
reduced risk of atherosclerosis and obesity
How much does red meat daily increase morality?
15-20%
What amount of DM is linked to obesity?
80%
What is the highest risk BMI for DM?
> 35
What waist circumference has higher risk of DM?
> 40 men and >35 women
What occurs with DM and obesity?
impaired ability of insulin to regulate gluconeogenesis increase glucose increase LDL reduce HDL Hyperinsulinemia INFLAMMATION
How does obesity relate to osteoarthritis?
increase load –> articular cartilage
loss of skeletal muscles –> articular shock absorption
adipocytokines w/ synovial fluid
Is osteoarthritis just wear and tear?
no, also inflammatory
What is the most common type of osteoarthritis in obesity?
knee