Obesity Management Flashcards

1
Q

Obesity management includes

A

Dietary nutrition intervention
Medical nutrition therapy
PA
Behavioral approaches
Pharmacological agents
Surgery, psychotherapy

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2
Q

5As of obesity management

A

Ask permission

Assess their story: goals, classification and disease severity

Advise on management: medical nutrition therapy + exercise or psychological, medication, surgery…etc

Agree on goals

Assist with drivers/barriers

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3
Q

Edmonton Obesity Staging System (EOSS)

A

Stage 0: no signs or symptoms or limitations related to obesity

Stage 1: Subclinical risk factors, mild symptoms or mild psychological issues which impair wellbeing

Stage 2: Established obesity-related comorbidities, moderate limitations or moderate psychological issues

Stage 3: Significant obesity related organ damage, psych, functional limitation or impairment of wellbeing

Stage 4: Severe obesity-related comorbidities, disabling psych symptoms or functional limitations

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4
Q

4Ms of obesity

A

During assessment address: Mental, mechanical, metabolic and monetary drivers/complications/barriers to weight management

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5
Q

Guiding principles for practitioners around obesity management

A

Obesity is a chronic disease and must be addressed by improving health not focusing on weight - improve health outcomes

Early interventions address root causes and remove roadblocks

Best weight may not equal ideal weight

Emphasize positive relationships with food as energy restriction is not sustainable long term

People with obesity at increased risk of micronutrient deficiencies

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6
Q

Non-weight based health indicators to evaluate nutrition interventions with clients

Medical nutrition therapy goals

A

Cognitive improvements, energy, functional improvements, medical, body composition, appetite related and mental health

changes in eating behavior, weight loss/stabilization, risk reduction, complications reduction, eligibility for surgery and psychosocial adjustment

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7
Q

Weight loss benefits in terms of chronic disease risk reduction

A

Improved glucose tolerance, insulin sensitivity, blood pressure/volume/CO, sympathetic activity

Normalized TAGs, HDL/LDL ratio

Decreased reliance on meds for glucose lowering, antihypertensive and antihyperlipidemic

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8
Q

Rule of thumb to estimate energy deficit for weight loss?

How is kcal restriction determined?

Limitations to this rule of thumb method

A

calculate REE, then TEE (using PAL)

subtract 500 kcal from TEE

Calculation: 1lb (454g) WAT = 87% fat = 395g fat = 3500 kcal per week –> -500 kcal/day or -300 kcal/day for slower/more sustainable loss

Limitations: assumes all weight lost is fat, LBM also will be lost, loss is not linear bc plateaus and ↓ REE

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9
Q

How to estimate a target weight?

A

If loss goal is 10 kg, map out .5 kg loss per week

Aim for a healthy BMI (upper range)

Aim for a modest loss first 5-10%

Best weight is the weight you can achieve while living a healthy lifestyle you can enjoy

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10
Q

Nutrient needs during caloric restriction

Protein requirements

Protein/GI combo effect on weight maintenance

A

<1200 kcal requires multivitamin supplementation

Protein requirement increases with decreasing calories
–> produces greater reduction in body weight/fat mass and serum TAGs without as much LBM loss (better REE)

While fat decreases (only linoleic acid supplementation at very low kcal)

High protein-low GI shows best weight maintenance over time while all other combinations have weight re-gain
- but not difference in perceived satiety

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11
Q

Common features of National Weight Control Registry

A

Most have a low energy, low-fat diet with minimal variation
Exercise average 1hr per day
Eat breakfast
Weigh themselves
Watch less than 10hrs of TV per week

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12
Q

Priorities for a balanced diet

A

No ideal diet or approach

Increase diet quality
Energy deficit
Avoid nutritional deficiencies
Preserve lean mass
Promote long-term adherence
Behavioral and dietary change for life

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13
Q

Health benefits of exercise

PA + diet restriction results

A

Active adults have 20-35% lower risk of premature mortality

Modest enhancement in PA in sedentary individuals has large improvement in health status

Rates of chronic disease and cancer drop with increasing PA

PA will increase weight loss only if diet restriction is not too severe
Resistance training + caloric restriction is effective for weight loss and retaining LBM during energy restriction

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14
Q

What are the 24hr movement guidelines for 18-64 and 65+

A

18-64: variety, mod-vig 150 min/week, resistance training 2x per week, several hours light activity, 7-9hrs sleep, <3hr recreational screen time (<8hrs sedentary time)

65+: variety, mod-vig 150 min/week, resistance training 2x per week, challenge balance, several hours light activity (standing), 7-8 hours sleep, <3hr recreational screen time (<8hrs sedentary time)

Difference is including balance challenge and a little less sleep required

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15
Q

Elements of behavioral change

Readiness assessment

Path to Desirable Eating Behavior:

A

Behavioral change:
↑ awareness (food diaries)
↑ PA, alter attitudes (behavior chain of negative triggers –> change the narrative!)
Develop support systems
Nutrition education and literacy

Readiness assessment to address behavioral, psychological and environmental readiness for change

Path to Desirable Eating Behavior: Build coping skills –> prevent mistakes –> increase confidence –> long term control

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16
Q

Permissive vs restraint thoughts

Self-critical vs resilient thoughts

A

Permissive: associating food with reward
Restraint: acknowledging the craving but knowing the consequences of how it will make you feel

Self-critical: blaming yourself and finding excuses
Resilience: Acknowledging the challenge, knowing it is hard but finding a way to move forward

17
Q

Macronutrient distributions during weight loss and maintenance

A

Protein WL: 25-30% of kcal, 15-20% during maintenance (10-35% base)

CHO: 45-65% favoring whole grains and low sugar

<30% total fat including EFAs and low saturated + trans fats

Consider meal replacements + education for an energy reduced diet

18
Q

Pharmacological agents approved in Canada

A

Liraglutide

Naltrexone/Bupropion

Orlistat

Semaglutide

19
Q

Orlistat mode of action, effect and side effects

A

Mode of Action: lipase inhibitor - produces malabsorption of 30% fats if taken before a meal

Effect: promotes weight loss, improves BP, lipids and glycemia

Side effects: fatty stools, fecal urgency, incontinence, loss of fat soluble vitamins requiring supplementation

$$

20
Q

Naltrexone/Bupropion mode of action, effect and side effect

A

Mode of Action: opioid receptor agonist + antidepressant (dopamine reuptake inhibitor) given in combo to induce satiety, and reduce cravings by influencing reward system

Effect: weight loss, improved lipids, glycemia but ↑ BP (contraindicated for hypertension)

Side effects: nausea, constipation, headaches, dry mouth, dizziness, diarrhea, contraindications

$$$

21
Q

Liraglutide mode of action, effect and side effect

A

Mode of Action: glucagon-like-peptide 1 analog acts on POMC/CART neurons to induce satiety, ↑ insulin and ↓ glucagon during fed state

Effect: weight loss, improved BP, lipids and glycemia

Side effects: Nausea, constipation, diarrhea, and vomiting

daily injection, $$$$

22
Q

Semaglutide mode of action, effect and side effect

A

Mode of Action: glucagon-like-peptide 1 analog acts on POMC/CART neurons to induce satiety, ↑ insulin and ↓ glucagon during fed state

Effect: glucagon-like-peptide 1 analog acts on POMC/CART neurons to induce satiety, ↑ insulin and ↓ glucagon during fed state

Side effects: Nausea, constipation, diarrhea, and vomiting

Weekly injection $$$$ (same molecule as ozempic)

Low dose for T2D management, higher for weight loss

23
Q

Tirzepatide mode of action and effect

A

Mode of action: GIP + GLP-1 agonist

Effect: stimulates release of insulin from β cells in pancreas –> higher weight loss than semaglutide