Obesity James Levy

Question 1

Biggest contributor to obesity?

Answer 1

Genetics

Question 2

BMR is determined by? Gender considerations?

Answer 2

lean body mass : muscle and bones

men higher BMR than women

Question 3

Most variable of energy expenditure is ?

Answer 3

Exercise

Question 4

When you lose weight, what happens to your BMR?

Answer 4

BMR slows down

Question 5

Where is our appetite center located?

Answer 5

In the HP, arcurate nucleus and lateral nucleus

Question 6

alpha MSH binds to what to inhibit appetite?

Answer 6

MC4R protein

Question 7

What inhibits binding of alpha MSH?

Answer 7

Agouti-related protein

Question 8

What is role of leptin?

Answer 8

Leptin activates POMC in neurons and inhibit appetite

Question 9

What are most cases of obesity consist of when concerning leptin?

Answer 9

Leptin resistance

Question 10

What substance rises when before you eat? Where does it stimulate?

Answer 10

Ghrelin stimulates the NPY/AGRP

Question 11

What increases after eating? Where does it stimulate?

Answer 11

PYY inhibits the stimulatory pathway

Question 12

Which molecules slow gastric emptying?

Answer 12

Cholecystikinin
amylin
incretins