Obesity Flashcards
What are the limitations of BMI?
Body mass index (BMI) is a simple index of weight-for-height that is commonly used to classify overweight and obesity in adults.
BMI is defined as a person’s weight in kilograms divided by the square of his height in meters (kg/m2).
BMI doesn’t take into account muscle mass, but only kg and height. Usually, people with more muscle mass will have more kg than those with fat.
Why is microbiota important?
The gut of an individual is inhabited by trillions of microbes that play a significant role in host energy homeostasis through their symbiotic interactions.
Dysbiosis in gut microbiota causes disequilibrium in energy homeostasis that ultimately leads to obesity.
Numerous mechanisms have been reported by which gut microbiota induces obesity in experimental models. However, which microbial community is directly linked to obesity is still unknown
Due to the complex nature of gut microbiota. Prebiotics and probiotics are the safer and more effective dietary substances available, which can therapeutically alter the gut microbiota of the host.
Further, the therapeutic approaches (prebiotics/probiotics) that helped in positively altering the gut microbiota
Why can fat cells easily enter the cell compared to proteins and sugars?
Proteins and carbs need receptors (such as protein channels
0 to enter the cell because they are more hydrophilic, while fat cells don’t, and they can directly enter the cell membrane, which is also made of a lipid bilayer, this allows fats to passively diffuse through the membrane.
What are the negatives of gastric bypass?
Gastric bypass can lead to malabsorption of essential nutrients, necessitating lifelong supplementation and monitoring.
Over time, some individuals may regain weight due to dietary choices or stretching of the stomach pouch.
As with any surgery, there are inherent risks, including infection, bleeding, and complications related to anesthesia.
Where do the fatty cells come from?
Fibroblasts (from bone cells initially).
