Obesity

Question 1

Weight loss in obesity leads to reduced satiety by a number of mechanisms ?

Answer 1

Reduced leptin (satiety hormones)

Question 2

Weight loss in obesity leads to reduced satiety by a number of mechanisms ?

Answer 2

Increased hunger hormones (ghrelin)

Question 3

Weight loss in obesity leads to reduced satiety by a number of mechanisms ?

Answer 3

Increased neural activity associated with processing food- related stimuli
(Neurpeptide Y)

Question 4

Weight loss in obesity leads to reduced satiety by a number of mechanisms ?

Answer 4

Decreased neural activity associated with retaining responses to food (cholecystokinin)

Question 5

Leptin tell the brain?

Answer 5

You are full

Question 6

Hungry hormone

Answer 6

Ghrelin

Question 7

Ghrelin tells us we are…

Answer 7

Hungry

Question 8

Where is leptin secreted from?

Answer 8

Adipose tissue

Question 9

Ghrelin is located in the?

Answer 9

G cell / stomach

Question 10

Where is insulin, amylin secreted from?

Answer 10

B cells/ pancreas

Question 11

Where in the brain is the appetite centre?

Answer 11

Hypothalamus

Question 12

Why is GLP-1 relevant to appetite and weight maintenance?

Answer 12

Has actions on the gastrointestinal tract, It regulates appetite directly. It delays gastric emptying & gut motility

Question 13

Why is GLP-1 relevant to appetite and weight maintenance?

Answer 13

Regulates appetite & actions on the gastrointestinal tract

Question 14

What are the appetite suppressing neurons?

Answer 14

Gut peptides: GLP-1, PYY, CCK

Question 15

What does EOSS stand for?

Answer 15

Edmonton obesity staging system

Question 16

What Tool do you use to assess obesity?

Answer 16

EOSS
Edmonton obesity staging system

Question 17

How many stages has the eoss tool?

Answer 17

0, 1, 2, 3, 4

5

Question 18

What biochemistry markers should we check in patients with obesity?

Answer 18

D, iron, B12, folate

Question 19

What are the protein requirements for a person with obesity?

Answer 19

+1gm/kg/ IBW/day

Question 20

Possible dietary factors to consider for therapeutic assessment ( hypertention)

Answer 20

Salt, alcohol

Question 21

Possible dietary factors to consider for therapeutic assessment (NAFLD)

Answer 21

Alcohol, protein, salt, carb (quantity, quality), fluid restrictions

Question 22

Possible dietary factors to consider for therapeutic assessment (sarcopenia)

Answer 22

Protein

Question 23

Possible dietary factors to consider for therapeutic assessment (PCOS)

Answer 23

CHO (Q&Q), FAT type

Question 24

Possible dietary factors to consider for therapeutic assessment (CKD)

Answer 24

Protein, potassium, phosphate, salt, fluid restrictions

Question 25

Possible dietary factors to consider for therapeutic assessment (obstructive sleep apnoea)

Answer 25

Meal patterns, caffine

Question 26

Possible dietary factors to consider for therapeutic assessment (GORD)

Answer 26

Alcohol, spice, caffeine, fat quantity/ type

Question 27

Possible dietary factors to consider for therapeutic assessment (IBS)

Answer 27

Meal patterns, fibre type, probioics, caffeine influence

Question 28

What are the ways to achieve or manage satiety/ appetite

Answer 28

Increase protein, fibre, water, food volume, reduce glycaemic index, non distracting eating, pace eating

Question 29

When should liraglutite be discontinued?

Answer 29

D/c for patients who have not loss 5% r greater of initial body weight after 12 was on treatment at dose 3mg/ day

Question 30

Semaglutide affects what receptor?

Answer 30

GLP-1

Question 31

GLP-1 stands for ?

Answer 31

Glucagon like peptide 1

Question 32

Semaglutide blinds to GLP-1 receptor and does what?

Answer 32

Increases insulin secretion, suppress glucagon secretion, slows gastric emptying *reduces appetite

Question 33

Whay does orlistat do?

Answer 33

Reduces fat absorption by approx 30%. It partially inhibits hydrolysis of triglycerides &reduces absorption of monoaclglycerides & free fatty acids