Anit-platelet & Anti- Hypertensive Agents

Question 1

Haemostasis regulation refers to ……… in response injury or damaged blood vessels

Answer 1

Blood clotting

Question 2

Homeostasis & blood clothing action

Answer 2

1. Wound causes vasoconstriction
2. Adhesion & activation of platelets
3. Fibrin forms

Question 3

What is a thrombosis?

Answer 3

Pathological formation of a haemostatic plug within vascular system (vasculature)

Question 4

Cholesterol is important for?

Answer 4

Role in the precursor for steroid hormones, bile acids & important for structural integrity of cell membrane

Question 5

What is hyperlipidemia ?
Total cholesterol

Answer 5

Total cholesterol
Below 5.2mmol/L desirable
5.2-6.2 borderline high
Above 6.2 high

Question 6

Optimal LDL Cholesterol for those at high risk of HD?

Answer 6

Below 1.8mmol/L

Question 7

Optimal LDL Cholesterol for those at risk of HD ?

Answer 7

Below 2.6 mmol/L

Question 8

Near Optimal LDL Cholesterol?

Answer 8

2.6-3.3 mmol/L

Question 9

Borderline high LDL Cholesterol?

Answer 9

3.4-4.1mmol/L

Question 10

high LDL Cholesterol?

Answer 10

4.1-4.9mmol/l

Question 11

Very high LDL Cholesterol?

Answer 11

Above 4.6mmol/L

Question 12

Primary cause hyperlipidemia?

Answer 12

Genetic mutations

Question 13

Causes of secondary hyperlipidemia?

Answer 13

Nephritic syndrome
Obstructive jaundice
Hypothyroidism
Crushing syndrome
Anorexia nervosa
Thiazide diuretics
Ciclosporin

Question 14

Causes of mixed hyperlipidemia* ? (Increase in plasma cholesterol & triglycerides)

Answer 14

Dm2
Obesity
Alcohol excess
Monoclonal gammopathy
Renal dialysis
Glucocorticoids
Beta blockers
Retinoic acid derivatives

Question 15

What % rule * Positive correlation between serum cholesterol & CHD?

Answer 15

1-2% rule