OB Ch. 10 Fetal Development and genetics Flashcards

1
Q

Stages of Fetal Development

A

-zygotic stage
-blastocyst stage
-embryonic stage
-fetal stage

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2
Q

zygotic stage

A

-conception
-fertilization of egg via sperm
-sperm are determiner for sex (X or Y carrier)

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3
Q

fertilization occurs where

A

-fallopian tube
-zygote travels from fallopian tube to uterus via tubular movement

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4
Q

zygote undergoes cleavage and turns into…

A

-MORULA
-morula reached uterine cavity 72 hours after fertilization

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5
Q

Blastocyst stage

A

-morula cleaves and becomes more solid mass that attaches to uterine cavity
-nutrient rich fluid enters uterine cavity

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6
Q

inner surface of blastocyst forms..

A

embryo and amnion

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7
Q

trophoblast

A

-outer layer surrounding blastocyst
-attaches itself to endometrium for more nourishment
-will eventually attach itself to upper fundus d/t rich blood supply
-develops into chorion and helps form placenta

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8
Q

embryonic stage lasts from

A

end of 2nd week to 8th week
-major structures and organs begin to develop, main external features

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9
Q

ectoderm forms into

A

CNS, special senses, skin, glands, amnion

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10
Q

amnion is..

A

thin membrane filled with amniotic fluid

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11
Q

mesoderm forms…

A

skeletal, urinary, circulatory, and reproductive organs

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12
Q

ECTODERM forms…

A

respiratory system, liver, pancreas, digestive

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13
Q

fetal stage

A

differentiation and structures specialize by end of the 8th week

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14
Q

role of amniotic fluid

A

-thermoregulation for fetus
-permits symmetric growth and development
-cushion for fetus from trauma
-allows umbilical cord to be relatively free from compression

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15
Q

amniotic fluid derived from…

A

-fetal urine
-fluid from maternal blood source across amnion

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16
Q

amniotic fluid increases in volume throughout pregnancy. By term, should be

A

1000 mL or 1 L

17
Q

oligohydramnios

A

-decreased amniotic fluid
-500 mL or less
-DXed via ultrasound

18
Q

what conditions are associated with oligohydramnios

A

-uteroplacental insufficiency
-fetal renal abnormality

19
Q

Oligohydramnios: Fetus is at risk for

A

-low birth weight
-surgical birth

20
Q

Polyhydramnios

A

-excess amniotic fluid
-2 L or more at birth
-DXed with ultrasound

21
Q

what conditions are associated with polyhydramnios

A

-maternal diabetes
-neural tube defects
-chromosomal deviations
-malformations of GI or CNS

22
Q

Polyhydramnios: fetus at risk for…

A

premature rupture of fluid membranes d/t uterine overdistention

23
Q

umbilical cord characteristics

A

-formed from amnion
-contains 1 large vein and 2 small arteries

24
Q

Wharton jelly is…

A

-white jelly surrounding all 3 blood vessels in umbilical cord to prevent compression
-if cord compresses, blood supply and nutrients would be cut off to fetus

25
Q

Maternal uterine arteries deliver…

A

nutrients to placenta

26
Q

Maternal uterine vein carries…

A

fetal waste products away

27
Q

Placenta Functions

A

-serves as interface between mother and fetus
-if something is wrong with placenta…something is wrong with fetus
-produces hormones to control physiology of mother to ensure fetus is supplied with adequate nutrients and O2 for growth
-placenta acts as lungs during gestation; fetal rungs are non functional
-protect fetus from immune attack by the mother
-remove waste products from fetus
-induce mother to bring more nutrients to placenta
-promotes hormones that mature into fetal organs

28
Q

Placenta Characteristics

A

-formed by week 12
-rough side faces mother (amniotic membrane)
-smooth side faces baby

29
Q

Do maternal and fetal blood mix?

A

NO! they should not mix d/t placental barrier

30
Q

what is the placental barrier

A

fetal tissues that separate the materal and fetal blood

31
Q

Shunt does what?

A

-delivers oxygen rich venous blood to systemic circulation and ensures that oxygen poor venous blood bypasses pulmonary circulation

32
Q

when does lung development finish?

A

AT BIRTH

33
Q

fetal circulation pathway for oxygenated blood

A

-oxygen rich blood carried from placenta to fetus via umbilical vein
-half goes to hepatic arteries, other half goes to ductus venosus in IVC
-blood from vena cava deflected via foramen ovale into LA –> LV –> ascending aorta –> head and upper body

34
Q

fetal circulation pathway for deoxygenated blood

A

-SVC–> RA–> RV –> pulmonary artery –> ductus arteriosus –> descending aorta –> placenta (for oxygenation)
-only 5-10% of blood goes to lungs d/t pulmonary resistance b/c fetal lungs are filled with fluid and nonfunctional

35
Q

what happens to lungs at birth

A

-with first breath, lungs inflate, leads to increase in blood flow from lungs to RV
-pressure increases in LA (left side of foramen ovale presses against opening and creates functional separation between 2 atria)
-blood goes to RV as it can no longer be bypassed (reason for increased blood flow to lungs)
-RV pumps blood into pulmonary artery, which goes to lungs for oxygenation and back to LV