OB BM4 LONG EXAM2: Flashcards by SALI BABY

When is pulmonary embolism shown to be most common during gestation?

Second trimester
Between 32-33 weeks AOG
On the 6 weeks postpartum
Immediately after delivery

On the 6 weeks postpartum

How well did you know this?

Not at all

Perfectly

Which of the statements is true regarding hypercoagulability of blood during pregnancy?

a. There is progressive increase of Factor XI
b. There is an increase in resistance to activated protein C
c. Fibrinolytic Inhibitors activity is decreased during pregnancy
d. Protein S increases progressively during pregnancy

b. There is an increase in resistance to activated protein C

How well did you know this?

Not at all

Perfectly

Which thromboembolic disorder is considered lethal?

Homozygous Antithrombin deficiency
Heterozygous Prothrombin G20210A mutation
Homozygous Protein C or S deficiency
Heterozygous Factor V inheritance

Homozygous Antithrombin deficiency

How well did you know this?

Not at all

Perfectly

Which vitamin is associated with elevated homocysteine levels secondary to autosomal recessive inheritence of C6671 ___table mutation

Vit B1
Vit D
Vit B9
Vit B6

Vit B9 - kani daw sa ans key

How well did you know this?

Not at all

Perfectly

One of the adverse pregnancy complications of antiphospholipid antibody syndrome

abruptio placenta
gestational diabetes
postpartum hemorrhages
perinatal death

perinatal death

How well did you know this?

Not at all

Perfectly

Which one is an obstetrical risk factor for thromboembolism?

connective tissue disorder
obesity
multiparity
thrombophilia

multiparity

How well did you know this?

Not at all

Perfectly

What coagulation factor does Protein S inactivate?

Factor VIIa
Factor VIIIa
Factor IXa
Factor Xa

Factor VIIIa

How well did you know this?

Not at all

Perfectly

When is the best time to perform screening for thrombophilia?

At the first trimester
During hormonal therapy
When patient is not pregnant
At the early third trimester

When patient is not pregnant

How well did you know this?

Not at all

Perfectly

The most common location of deep vein thrombosis is:

iliac vein
iliofemoral vein
calf vein
saphenous vein

iliofemoral vein

How well did you know this?

Not at all

Perfectly

What is the common side effect of warfarin treatment as its anti-protein C effects?

Paradoxical thrombosis
hemorrhage
Decreased INR activity
Fetal malformation

Paradoxical thrombosis

How well did you know this?

Not at all

Perfectly

One of which is a vascular change in pregnancy

Melasma
Palmar erythema
Striae gravidarum
Linea nigra

Palmar erythema

How well did you know this?

Not at all

Perfectly

Which among these diseases is improved during pregnancy?

Porphyria cutanea tarda
pseudoxanthoma elasticum
Hidradenitis suppurativa
Acrodermatitis enteropathica

Hidradenitis suppurativa

How well did you know this?

Not at all

Perfectly

These are characterized as 1-5mm pruritic red papules on the extensor surfaces and trunk

Eczema of pregnancy
Pruritic folliculitis of pregnancy
Pemphigoid gestationis
Prurigo of pregnancy

Prurigo of pregnancy

How well did you know this?

Not at all

Perfectly

What body part does pemphigoid gestationis begin to occur?

extremities
face
palms
Abdomen

extremities

How well did you know this?

Not at all

Perfectly

Differential diagnosis of pemphigoid gestationis

Atopic dermatitis
Urticarial allergic reactions
Erythema multiforme
Viral Exanthema

Erythema multiforme

How well did you know this?

Not at all

Perfectly

Where do we usually see lesions of PUPPP?

Arms
Umbilicus
Striae
Legs

Striae

How well did you know this?

Not at all

Perfectly

What is the pathophysiology of PUPP?

Increase level of fetal DNA
Binding of the IgG antibodies to the lumina lucida
Mutation of genes encoding for protein transport
Hormonally mediated

Increase level of fetal DNA

How well did you know this?

Not at all

Perfectly

Which is a differential diagnosis of Intrahepatic cholestasis of pregnancy?

Uremia
Atopic dermatitis
Pemphigoid gestationis
Erythema multiforme

Uremia

How well did you know this?

Not at all

Perfectly

Which statement is true regarding pruritic folliculitis of pregnancy?

Lesions often spares the umbilicus
The cause is unknown
One of the differentials is PUPP
Treatment includes antihistamine

The cause is unknown

How well did you know this?

Not at all

Perfectly

This condition is characterized as erythematous plaques with pustules seen on the inner thigh and spread to the trunk:

Pemphigoid gestationis
Intrahepatic cholestasis
Impetigo herpetiformis
Erythema multiforme

Impetigo herpetiformis

How well did you know this?

Not at all

Perfectly

Multiparous women have low risk for which type of malignancies?

Ovarian cancer
Cervical cancer
Lymphoma
Thryoid cancer

Ovarian cancer

Exposure to radiotherapy during pregnancy would lead to CNS disorders in the fetus, what is the threshold dose for intellectual disability at 20 weeks AOG?

0.01 Gy
0.05 Gy
0.10 Gy
0.25 Gy

0.25 Gy

To prevent undue risk for infection what is the recommended management for chemotherapy

Should be avoided at first trimester
Patient should be given empirical dose of antibiotics
Withheld 3 weeks prior to delivery
Start immediately postpartum

withheld 3 weeks prior to delivery

This therapy inhibits the human epidermal growth factor type 2

Targeted Tyrosine kinase
Monoclonal antibodies
Small molecular inhibitors
Molecular therapy

Monoclonal antibodies

One of these malignancies can metastasize to the placenta: breast cancer endometrial cancer uterine sarcoma ovarian cancer

breast cancer

This is a ferric substance that can be applied with pressure to the stalk stub for hemostasis after polypectomy policresulen concentrate albothyl ointment Monsel paste Cryoprecipitation

Monsel paste

Which statement is true regarding screening guidelines for epithelial neoplasia? a. HPV cytology should be done starting at 31 years old b. screening should start at 21 years old or once sexually active c. cytology should be done every year from 21-29 years of age d. cytology co-testing is done every 3 years onward after 30 years old

a. HPV cytology should be done starting at 31 years old

What is the management for a 25 y/o pregnant woman at 30 weeks AOG with stage 2A cervical carcinoma? a. radical hysterectomy after chemotherapy b. neoadjuvant therapy prior to surgery c. hysterotomy then radical hysterectomy d. delay treatment until term then chemoradiation

b. neoadjuvant therapy prior to surgery

# [](http://) The most common type of fibroid degeneration during pregnancy is: hyaline myxomatous calcific carneous

carneous

What is the recommended diagnostic modality for pregnancy luteoma? MRI ultrasonography serum testosterone doppler/color flow

serum testosterone

Which organ is primarily involved in Hodgkin’s lymphoma stage 2? spleen thymus mediastinum bone marrow

mediastinum

What is the recommended treatment for acute myeloid leukemia in pregnancy? delay therapy until delivery chemotherapy at any trimester early abortion multiagent chemotherapy after first trimester

early abortion

What is the strongest determinant of survival in malignant melanoma during pregnancy? age of gestation of diagnosis clinical stage of the disease prompt and early treatment timing of therapeutic abortion

clinical stage of the disease

When do we expect fetal antibodies level to be same with the mother's antibodies? 9-15 weeks AOG 16 weeks AOG 12-14 weeks AOG 26 weeks

26 weeks

When does fetal infection occur with cytomegalovirus? During amniocentesis At Third trimester During delivery Immediate Postpartum

During delivery

How would you interpret the CMV serological test with high IgG avidity but non-reactive with IgM? Primary infection Infection is unlikely Low risk for infection Past infection

Past infection

What is the incubation period of Varicella Zoster Infection in pregnant women? 4 days prior to lesions 14 days 2 days 7 days

14 days

Recommended diagnostic test for Herpes simplex infection in pregnancy? Polymerase chain reaction Indirect fluorescent antibodies Latex agglutination Fluorescent antibodies

Polymerase chain reaction

This viral infection is caused by an RNA togavirus with a period of infectivity of 1 week before rashes occur: Rubella Herpes Simplex Rubeola Varicella Zoster

Rubella

The risk of congenital malformation with vertical transmission of Congenital Rubella syndrome at ???? weeks AOG is: 33% 90% 11% 50%

50% ?

The mainstay test for the diagnosis of rubella infection is: Rapid agglutination assay Direct fluorescent antibody test Hemagglutination Inhibition assay Immune adherence agglutination test

Hemagglutination Inhibition assay

The main congenital anomaly that can be seen in mumps infection is Endocardial fibro elastosis Microcephaly Chorioretinitis Hepatosplenomegaly

Endocardial fibro elastosis

Transmission of syphilis to the fetus usually occur at what AOG 15 weeks AOG 17 weeks AOG 19 weeks AOG 21 weeks AOG

17 weeks AOG

Which other condition can also manifest reactivity to non-treponemal test? Herpes Leukemia Lymphoma Tuberculosis

Lymphoma

What medication can be given to neonates born to mother with active pulmonary tuberculosis Etambutol Pyrazinamide Isoniazid Rifampicin

Isoniazid

What is the recommendation for vaccination of pregnant women? Varicella vaccine can be given after the first trimester Tetanus toxoid should be given at 27 weeks AOG HepA vaccine is recommended if otherwise indicated LAV influenza is recommended at any trimester

HepA vaccine is recommended if otherwise indicated

This is true regarding tetanus vaccine Should be given to infants starting 5 months Booster dose should be given to children at 4 years old Additional booster of tetanus vaccine should be given at 12 years old Continued booster doses should be given every 5 years

Additional booster of tetanus vaccine should be given at 12 years old

Tdap immunization at 27 weeks AOG should be given as follows: Booster if more than 3 years after last dose of tetanus toxoid Should replace TD at 24-26 weeks AOG Should be starte

Should replace TD at 24-26 weeks AOG

Hepatitis B vaccination is recommended for high-risk pregnant patients such as : young individuals had history of blood transfusion with promiscuous partner HIV positive patients

with promiscuous partner

Which is true regarding general recommendation if immunization during pregnancy? a. Inactivated and Live Vaccine b. can be given with precaution c. Immunization of household members is a must to prevent infection d. Termination of pregnancy warrants prevention of congenital infections Pregnancy test is a must before giving immunizations

Immunization of household members is a must to prevent infection