Bladder Pain Syndrome

Question 1

defined as the complaint of suprapubic or retropubic pain, pressure, or discomfort related to the bladder.

• usually increases in intensity with bladder filling and may persist or disappear after voiding

• have other associated urinary symptoms, such as urinary urgency or frequency;

Answer 1

Bladder pain syndrome

Question 2

Ulceration of the bladder wall

Answer 2

Hunner lesion

Question 3

associated with a defective glycosaminoglycan sulfate layer that covers the bladder mucosa

Answer 3

Interstitial cystitis

Question 4

Bladder pain syndrome is a diagnosis of:

Answer 4

Exclusion

Question 5

Differential diagnosis of bladder pain syndrome

Answer 5

-chronic or recurrent UTI
-urethral diverticulum
-vulvovaginal atrophic, inflammatory, allergic, or infectious condition
-chronic pelvic pain r/t endometriosis, inflammatory bowel conditions, myofascial pain and other

Question 6

Used for patients with painful bladder syndrome for pain or bladder spasm relief

Answer 6

Urinary analgesics

Question 7

Mixture of methenamine, methylene blue, phenyl salicylate, benzoic acid and hyoscyamine

Answer 7

Prosed DS

Question 8

Tricyclic antidepressant, beneficial only when a dose of 50 mg or more is achieved

Answer 8

Amitryptyline

Question 9

An FDA approved heparinoid medication to treat women with bladder pain syndrome/interstitial cystitis

Answer 9

Pentosan polysulfate (elmiron)

100 mg TID X 3 months