OAB & Urinary Rentention Flashcards

1
Q

The main function of bladder is to:

A

Store and expel urine

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2
Q

Which body part contracts to notify the brain that the bladder is filling with urine?

A

Detrusor muscle

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3
Q

When the bladder nears storage capacity, which type of signals are sent from the bladder to the brain?

A

Afferent

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4
Q

The ____ runs form the spinal cord to the appendages and you have to consciously and voluntarily make this system move or work.

A

Peripheral nervous system

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5
Q

The ____ is a large, triangular bone at the base of the spine and at the upper and back part of the pelvic cavity, where it is inserted like a wedge between the two hip bones.

A

Sacrum

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6
Q

_____ is the neurotransmitter in the parasympathetic nervous system that stimulates the muscarinic receptors

A

Acetylcholine or ACH

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7
Q

______ are labeled sacral nerves

A

Sacral nerves

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8
Q

In your own words, explain how normal storage and voiding function works.

A

As the bladder fills with urine, the destrusor muscle relaxes and the pelvic floor contracts.

Afferent signals are sent fro the bladder to the brain at the unconscious level.

When the conscious decision to void is made, efferent nerve impulses are sent from the brain to the bladder.

The pelvic floor relaxes and the detrusor muscle contracts. Urine is expelled from the body.

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9
Q

Which muscarinic receptors are found in the bladder and primarily responsible for voiding behavior?

A

M2 and M3

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10
Q

______ trigger reflex voiding in response to noxious stimuli

A

C fibers

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11
Q

Which statement is incorrect?

  • Normal storage relies on efferent signals to the bladder from the pontine micturition center of the brain
  • Acetylcholine attaches to M2 and M3 muscarinic receptors, initiating bladder contraction
  • under voluntary voiding activity in cerebrum, the external urinary sphincter, pelvic floor muscles, and detrusor muscles relaxes, allowing the bladder to empty completely of urine.
  • the average void is approximately 360cc and there is typically less than 100cc left in the bladder after voiding
A

under voluntary voiding activity in cerebrum, the external urinary sphincter, pelvic floor muscles, and detrusor muscles relaxes, allowing the bladder to empty completely of urine.

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12
Q

True/false:

A contraction of the detrusor muscle is what informs the brain that there is a need to void

A

True

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13
Q

T/F

Urine enters the bladder through the urethra

A

False

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14
Q

T/F

The trigone connects the ureteral orifices and the bladder neck

A

True

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15
Q

T/F

Muscles in the external urinary sphincter are under voluntary control

A

True

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16
Q

The main function of the bladder is to store urine? T/f

17
Q

When the bladder is filling with urine, afferent signals are sent from the bladder to the brain. T/f

18
Q

When the cerebral cortex is the area of the brain responsible for bladder control. T/f

19
Q

The release of the ACh in the synapses binds with the M2 and M3 muscarinic receptors in the bladder, which causes a contraction of the detrusor muscle. T/F

20
Q

Enteric nerves of the autonomic nervous system are directly responsible for controlling the gastrointestinal system and bowel

21
Q

Urgency incontinence

A

The involuntary loss of urine sometimes associated with a sudden strong desire to void

22
Q

Urgency frequency

A

An uncontrollable urge to urinate resulting in frequent, small amounts of urine. Posed as often as every 15 minutes

23
Q

Urinary retention

A

The inability to empty bladder or initiate a void (urine is retained in the bladder)

24
Q

Overactive bladder

A

Urinary urge incontinence or urgency frequency, occurring either alone or in combination. When the detrusor muscle in the bladder receives a sudden involuntary signals to contact before you are ready to urinate

25
Stress incontinence
The involuntary loss of urine during coughing, sneezing, laughing or other physical activities that increase intra-abdominal pressure.
26
What are symptoms of aob?
Urgency frequency Urge incontinence Noctura
27
What % of the us population is thought to have OAB?
16%
28
When is OAB considered a normal condition
It should never be considered a normal condition
29
What is the definition of urgency you frequency?
An uncontrollable urge to urinate that results in frequent, small amounts of urine voided
30
What are the primary symptoms of AOB?
Urgency frequency and urge incontinence
31
What are the two western studies that defined prevelance of OAB?
Milton and Noble
32
What is urodynamics
An assessment of how the bladder and urethra are performing their job of storing and releasing urine
33
T/f OAB medications are classified as antimuscarinic drugs
True
34
What’s nerves signals do OAB medications affect?
Efferent signals
35
Which of the following would be a treatment of last resort for urge incontinence?
Cycstectomy
36
How effective are OAB meds in treating voiding dysfunction?
- 37% of patient did not refill their prescription during 6 month follow up - 78% were unable to remain on their medication for longer than 150 days
37
What do you see as key side effects of OAB meds?
-side effects from inhibition of M2 and M3 receptors - blurred vision - dry mouth - dry eyes - constipation - dyspepsia (stomach and gall bladder) - tachycardia