OA/ DEGENERATIVE JOINT DISEASE

Question 1

Commonly known as degenerative joint disease

Answer 1

Osteoarthritis

Question 2

is a disorder that occurs in the synovial joints and results in progressive degeneration of the articular cartilage and subchondral bone

Answer 2

Osteoarthritis

Question 3

a progression of synovial and capsular thickening, ligamentous changes and possible joint effusion.

Answer 3

Osteoarthritis

Question 4

There is eventual bony remodelling and overgrowth at the margins of the joint

Answer 4

Osteoarthritis

Question 5

a bony juxta-articular outgrowth or nodule

Answer 5

Osteophytes

Question 6

you would see Osteophytes in which stage of OA?

Answer 6

Later Stage

Question 7

conversion of bone into a hard, ivory-like mass

Answer 7

Eburnation

Question 8

the bony overgrowth in OA

Answer 8

Spurring and lipping

Question 9

Inflammation of the synovium

Answer 9

Synovitis

Question 10

vertical clefts in the cartilage

Answer 10

Fissures

Question 11

T/F

OA is no longer viewed as a prototypical degenerative disease
resulting from normal bodily wear and tear

Answer 11

TRUE

Question 12

This is a multifactorial disorder in which

low-grade, chronic inflammation has a central role

Answer 12

OA

Question 13

T/F

Inflammation does NOT come into play early
in the course of OA, as a result of interactions between the immune system and factors including local tissue damage and metabolic dysfunction?

Answer 13

FALSE

IT DOES

Question 14

The histological findings of osteoarthritis consist of degenerative changes within the cartilage and the subchondral bone. There are changes in water and proteoglycan content within the cartilage. The cartilage becomes more fragile and more susceptible to mechanical disruption, which promote further abnormal stress on the joint leading to cartilage degeneration. As the cartilage wears, the underlying bone becomes fissured and also thickens.

Answer 14

Pathogenesis

Question 15

stage is where fine flakes of superficial cartilage become loosened and flake off

Answer 15

Fibrillation

Question 16

appear in the cartilage and eventually run through the full thickness of the cartilage.

Answer 16

Fissures

Question 17

(inflammation of the synovium), synovial fluid may be forced into small cracks that appear in the bone’s surface, which produces large cysts. There is loss of articular cartilage/subchondral bone

Answer 17

Synovitis

Question 18

Reactive juxta-articular bony nodules are formed and create the following: Eburnation, spurring, and lipping. Name bony nodule(s)

Answer 18

Osteophytes